Skip to main content

10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

ADVERTISEMENT
Identification
Molecular formula
C16H16FN
CAS number
3427-28-9
IUPAC name
(6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
State
State
At room temperature, the compound is in a solid state. It maintains a stable form under standard conditions and does not readily subliminate, consistent with many other similar heterocyclic compounds.
Melting point (Celsius)
152.50
Melting point (Kelvin)
425.65
Boiling point (Celsius)
431.22
Boiling point (Kelvin)
704.37
General information
Molecular weight
253.30g/mol
Molar mass
253.3040g/mol
Density
1.1462g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. Its appearance is consistent with typical organic solid heterocycles which may exhibit some variation in color intensity based on purity.

Comment on solubility

Solubility Characteristics

The solubility of (6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline can be quite complex due to its unique molecular structure and the presence of multiple aromatic rings.

General Solubility Insights

In general, the solubility of compounds like this one can be influenced by several factors:

  • Polarity: As a largely non-polar compound, it is expected to have low solubility in polar solvents such as water.
  • Solvent Compatibility: Better solubility is likely in non-polar organic solvents (e.g., hexane, chloroform) due to the hydrophobic nature of the fused aromatic rings.
  • Functional Groups: The presence of a fluoro group may enhance solubility in certain organic solvents while also affecting the overall molecular interactions.

Experimental Considerations

When examining the solubility of this compound, it is crucial to consider the following:

  • Temperature: Increased temperatures often lead to increased solubility in many solvents.
  • pH Levels: Variations in pH could potentially alter solubility if the compound contains acidic or basic functional groups, though this is less likely with the current structure.
  • Concentration Limits: Be cautious of the concentration limits in different solvents, as high concentrations may lead to precipitation.

In conclusion, while specific solubility values may vary, understanding the interplay of structural features and environmental conditions can offer significant insights into the solubility behavior of (6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline.

Interesting facts

Interesting Facts about (6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

(6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline is a captivating compound with diverse applications and properties that can intrigue both scientists and students alike. Here are some fascinating points to consider:

  • Structural Complexity: This compound features a unique dibenzo structure that results in significant steric and electronic effects, which play a crucial role in its chemical behavior.
  • Fluorine’s Influence: The presence of the fluorine atom is particularly notable, as fluorine substitution often enhances a compound's biological activity and can improve its pharmacological properties. Fluorinated compounds are known for their increased stability and lipophilicity.
  • Pharmaceutical Relevance: Compounds similar to (6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline have been studied for their potential applications in medicinal chemistry, particularly in the development of antipsychotic agents and other therapeutic drugs.
  • Stereochemistry: The specific stereochemistry (6aS) can greatly influence the biological activity of the compound. Stereoisomers can exhibit different behaviors in biological systems, leading to varied therapeutic effects.
  • Research Significance: The ongoing research into dibenzoquinoline derivatives underlines their potential in various fields such as cancer research, neuroscience, and broader medicinal chemistry. Understanding these compounds can lead to advancements in drug design and development.

In conclusion, (6aS)-10-fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline is not just a simple chemical entity; it represents a crossroads of organic chemistry, pharmacology, and biochemistry. As researchers delve deeper into its properties and applications, it continues to pave the way for innovative therapeutic solutions.