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Aporphine alkaloid derivative

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Identification
Molecular formula
C26H27NO4
CAS number
Not Available
IUPAC name
[(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate
State
State

At room temperature, this compound is typically found as a crystalline solid. Its structural stability and aromatic nature contribute to its solid state under standard conditions of temperature and pressure.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.20
Boiling point (Celsius)
375.70
Boiling point (Kelvin)
648.90
General information
Molecular weight
421.50g/mol
Molar mass
421.4850g/mol
Density
1.2762g/cm3
Appearence

The compound generally appears as a solid, crystalline structure. It might possess a light yellowish to off-white color, depending on the environment and level of purity.

Comment on solubility

Solubility of [(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate

The solubility of the compound [(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate is influenced by its unique structure and functional groups. Understanding its solubility can be crucial for applications in pharmaceuticals and materials science. Here are several key points regarding its solubility:

  • Solvent Polarity: Like many organic compounds, the solubility in solvents usually increases with polarity. It may exhibit higher solubility in polar organic solvents such as methanol or acetone.
  • Hydrogen Bonding: The presence of the acetoxy group can engage in hydrogen bonding, potentially increasing solubility in alcohols.
  • Temperature Dependency: As with many compounds, solubility is likely to increase with temperature, allowing for more effective dissolution in various solvents.
  • Concentration Effects: At higher concentrations, the solubility limits may be reached, leading to precipitation; hence, careful consideration of concentration is essential in formulation.

In conclusion, the solubility of [(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate is a multifaceted characteristic, influenced by various environmental factors and its chemical structure. To improve solubility in practical applications, one might explore the use of additives or solubilizing agents.

Interesting facts

Interesting Facts about [(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] Acetate

This intriguing compound belongs to a class of organic molecules known for their complex structures and potential applications in medicinal chemistry. The name itself suggests a rich tapestry of functional groups and stereochemistry, making this compound a fascinating subject for both research and study.

Key Features

  • Stereo-selectivity: The designation of 6aS indicates a specific stereochemistry, which can play a crucial role in the biological activity of the compound. The functionality and orientation of its atoms can influence how the compound interacts with biological systems.
  • Acetoxy Groups: The presence of acetoxy groups suggests potential applications in drug design, as they may enhance lipid solubility and biological membrane permeability, impacting the compound’s efficacy as a therapeutic agent.
  • Complex Structure: The dibenzo structure indicates a polycyclic arrangement, which often correlates with interesting electronic properties. Such characteristics can lead to unique optical and electronic applications.

Applications and Research Potential

This compound is not only a marvel of structural ingenuity but also embodies the potential for innovation in various fields:

  • Medicinal Chemistry: Compounds similar to this one are often evaluated for their pharmacological properties, including anti-cancer activity, as they may inhibit certain pathways vital for tumor growth.
  • Natural Product Synthesis: Chemists are continually inspired by the structural diversity represented in natural products, leading to synthetic chemistries that aim to replicate or modify these compounds for enhanced activity.
  • Material Science: The unique properties of such complex molecules might find applications in organic electronics or sensors, where novel materials can yield significant advantages over traditional ones.

In summary, [(6aS)-11-acetoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate embodies the intricate beauty of organic chemistry, standing at the crossroads of structure and function. Its study not only enriches our understanding of chemical compounds but also paves the way for new discoveries in pharmaceutical and material sciences.

Synonyms
APORPHINE-10,11-DIOL, DIACETATE
DTXSID20171988
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, diacetate (ester)
5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)quinoline-10,11-diol diacetate (ester)
18720-24-6
DTXCID2094479
SCHEMBL12438791