Interesting facts
Interesting Facts about (6aS)-1,10-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
This compound, with its intricate structure, exhibits fascinating properties and applications that make it a subject of interest in the field of organic chemistry. Here are some engaging facts about it:
- Natural Occurrence: This compound is chemically related to several natural products, often found in plants and fungi, which serve as a source of inspiration for synthetic chemists looking to replicate their beneficial effects.
- Biological Activity: Various derivatives of dibenzoquinoline compounds have shown promising biological activities, including potential neuroprotective and anti-inflammatory effects. This sparks interest in their medicinal chemistry applications.
- Synthetic Challenges: The multi-step synthesis of this compound presents unique challenges. The elaborate process reflects the complexity often encountered in assembling multi-cyclic frameworks, revealing the art and science of organic synthesis.
- Diverse Applications: Its unique chemical structure implies potential applications in drug design, where specific modifications may enhance bioavailability or selectivity towards biological targets.
- Research Significance: Ongoing research into compounds like this one opens avenues for the development of new therapeutic agents, particularly in fields such as oncology and neurology.
- Structural Versatility: The presence of methoxy groups and a tetrahydro structure allows for various modifications, providing a platform for the development of analogs with tailored properties.
The exploration of compounds like (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol represents the intersection of biology, chemistry, and drug discovery, showcasing the potential for innovation within the realm of medicinal chemistry.
Synonyms
Boldine
Uniboldina
Boldin
(S)-Boldine
Boldine chloroform
1,10-Dimethoxy-2,9-dihydroxyaporphine
NSC 65689
EINECS 207-509-9
BRN 0094036
UNII-8I91GE2769
1,10-Dimethoxy-6a-alpha-aporphine-2,9-diol
8I91GE2769
6aalpha-Aporphine-2,9-diol, 1,10-dimethoxy-
5-21-06-00118 (Beilstein Handbook Reference)
4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-
6a-alpha-APORPHINE-2,9-DIOL, 1,10-DIMETHOXY-
2,6-dihydroxy-3,5-dimethoxyaporphine
BOLDINE (EP MONOGRAPH)
BOLDINE [EP MONOGRAPH]
NSC-65689
(6AS)-5,6,6A,7-TETRAHYDRO-1,10-DIMETHOXY-6-METHYL-4H-DIBENZO(DE,G)QUINOLINE-2,9-DIOL
4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-
1,10-dimethoxy-6aalpha-aporphine-2,9-diol
207-509-9
476-70-0
(+)-Boldine
(S)-(+)-Boldine
(6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
CHEBI:3148
CHEMBL388342
4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)-
4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)-
MFCD00135040
(S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
(+)-(S)-Boldine
2,9-Dihydroxy-1,10-dimethoxyaporphine
Aprophine alkaloid
Prestwick_46
Boldine (Standard)
BOLDINE [MI]
Prestwick3_000600
BOLDINE [WHO-DD]
Boldine, analytical standard
BSPBio_000480
cid_10154
MLS002153899
SCHEMBL177550
BPBio1_000528
cid_248507
HY-N6973R
DTXSID40883394
HMS2096H22
HMS2235B04
HY-N6973
TNP00245
BDBM50202318
MSK159059
s9050
ZB1855
Boldine, analytical reference material
AKOS015912953
CCG-208461
FB70015
5,6,6a,7-Tetrahydro-1,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-2,9-diol
NCGC00016454-01
NCGC00016454-02
NCGC00017314-01
NCGC00179547-01
AC-34043
AS-17759
CAS-476-70-0
SMR001233248
1ST159059
CS-0013445
NS00004847
C09365
1,10-Dimethoxy-6a-.alpha.-aporphine-2,9-diol
6a.alpha.-Aporphine-2,9-diol, 1,10-dimethoxy-
Q2070105
1,10-DIMETHOXY-6A.ALPHA.-APORPHINE-2,9-DIOL
BRD-K03440695-001-02-6
1,10-Dimethoxy-2,9-dihydroxyaporphine;ex Peumus boldus
Boldine, European Pharmacopoeia (EP) Reference Standard
1,10-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol, (S)-
(9S)-4,16-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.0(2),?.0(1)(3),(1)?]heptadeca-1(16),2,4,6,13(17),14-hexaene-5,15-diol
Solubility of (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
The solubility of the compound (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol can be influenced by various factors, primarily due to its complex molecular structure.
Key Factors Affecting Solubility:
Overall, the solubility pattern can be summarized as follows:
As a result, this compound may exhibit unique solubility behavior conducive to various applications, particularly in medicinal chemistry. Experimentation under controlled conditions is advised to obtain precise solubility measurements, as variations in temperature and pH can also impact its behavior.