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Sanguinarine

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Identification
Molecular formula
C20H15O4N
CAS number
2447-54-3
IUPAC name
(6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol
State
State

Sanguinarine is typically a solid at room temperature. It has a crystalline structure and a pale yellow color.

Melting point (Celsius)
265.00
Melting point (Kelvin)
538.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
331.34g/mol
Molar mass
332.3480g/mol
Density
1.3660g/cm3
Appearence

Sanguinarine appears as a pale yellow crystalline solid.

Comment on solubility

Solubility of (6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol

The solubility of the compound (6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol is an intriguing aspect worth exploring. Due to its unique structural features, particularly the presence of multiple methoxy groups, this compound exhibits varied solubility characteristics. Here are some notable points:

  • Polar Nature: The methoxy groups generally enhance the compound’s ability to dissolve in polar solvents such as water and alcohol.
  • Hydrophobic Interactions: The aromatic portions of the molecule can contribute to hydrophobic interactions, potentially leading to lower solubility in non-polar solvents.
  • Temperature Dependence: Solubility can be highly temperature-dependent, with varying behavior at different temperatures which could impact its application in various chemical reactions.
  • pH Sensitivity: Changes in pH may also affect solubility, particularly in biological or synthetic environments, where the compound may experience protonation or deprotonation.

In summary, understanding the solubility of this complex compound requires considering both its structural properties and the environmental conditions it is situated in. While it may dissolve more readily in certain polar solvents due to its methoxy substitutions, the structural characteristics can also lead to significant variations based on the medium used.

Interesting facts

Interesting Facts about (6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol

(6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol is a fascinating compound with intriguing properties and applications. Here are some notable aspects of this molecule:

  • Natural Product: This compound is often categorized as a natural alkaloid, derived from the plant kingdom.
  • Pharmacological Potential: Researchers are actively studying compounds like this one for their potential therapeutic effects. They may possess anti-inflammatory, antioxidant, or even neuroprotective properties.
  • Synthetic Challenges: The structural complexity of this molecule presents unique challenges in synthetic chemistry, often requiring innovative approaches to its synthesis.
  • Mechanism of Action: Ongoing studies aim to elucidate the specific mechanisms through which compounds of this type exhibit their biological activity, shedding light on their potential use in medicine.
  • Chemical Class: This compound belongs to the class of dibenzoquinolines, which are known for their interesting electronic properties due to the conjugated system of aromatic rings.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This sentiment resonates in the study of such complex compounds, inspiring chemists to explore the vast possibilities that await in the realm of organic chemistry.

As research progresses, it will be exciting to witness how (6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol contributes to the development of new medicines and our understanding of chemical interactions in biological systems.

Synonyms
Laurotetanine
Litsoeine
128-76-7
SDW3N623LN
DTXSID70904248
NSC-106610
RefChem:41047
DTXCID601333397
4,15,16-trimethoxy-10-azatetracyclo(7.7.1.0^(2,7).0^(13,17))heptadeca-1(17),2(7),3,5,13,15-hexaen-5-ol
1,2,10-trimethoxy-9-hydroxynoraporphine
(6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinoline-9-ol
1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinolin-9-ol
(+)-Laurotetanine
UNII-SDW3N623LN
NSC 106610
1,2,10-Trimethoxy-6a-alpha-noraporphin-6-ol
NSC 106610; Litsoeine; (+)-Laurotetanine
Laurotetanine impurity 1
LAUROTETANINE [MI]
6aalpha-Noraporphin-9-ol, 1,2,10-trimethoxy-
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-, (S)-
SCHEMBL905065
6a-alpha-NORAPORPHIN-9-OL, 1,2,10-TRIMETHOXY-
CHEMBL464098
orb1702084
CHEBI:175176
AKOS040747017
HY-117616
CS-0066642
H50838
Q27289154
(6aS)-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol
(6AS)-5,6,6A,7-TETRAHYDRO-1,2,10-TRIMETHOXY-4H-DIBENZO(DE,G)QUINOLIN-9-OL
4H-Dibenzo[de,g]quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-, (6aS)-