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Cephaeline

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Identification
Molecular formula
C20H24N2O4
CAS number
483-17-0
IUPAC name
(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol
State
State

At room temperature, cephaeline is typically found in a solid state. It is stable under normal conditions and does not evaporate readily, maintaining its crystalline form.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
458.15
Boiling point (Kelvin)
731.30
General information
Molecular weight
432.51g/mol
Molar mass
432.5130g/mol
Density
1.2500g/cm3
Appearence

Cephaeline appears as a white to off-white crystalline powder. It is notable for its glossy and shimmering facets under light, often resembling other crystalline alkaloids in texture and form.

Comment on solubility

Solubility of (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol

When considering the solubility of the compound (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol, several factors come into play due to its complex structure. This specific compound contains multiple methoxy groups as well as a fused ring system, both of which significantly influence its solubility characteristics. The following aspects are relevant:

  • Polarity: Given the presence of methoxy groups, the compound exhibits moderate polarity, which may enhance its solubility in polar solvents like methanol or water.
  • Hydrophobic Regions: The fused dibenzo ring structure contributes to hydrophobic characteristics, potentially reducing solubility in aqueous environments.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as dichloromethane or ethanol, aligning with similar compounds of high molecular weight.

In conclusion, predicting solubility is often challenging without empirical data. To sum up, one might say:

“The solubility of this intricate molecule may be competent in certain organic solvents while being limited in aqueous solutions.”

Experimental solubility tests are essential for confirming these theoretical predictions. Always consult literature for specific solubility data before use in practical applications.

Interesting facts

Interesting Facts about (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol

This intriguing compound, commonly referred to as a member of the dibenzoquinoline family, presents a unique blend of structural complexity and potential biological significance. Here are some fascinating insights into this compound:

  • Structural Diversity: The structure features a tetrahydro-dibenzo framework, which contributes to its unique properties. The presence of multiple methoxy groups enhances its solubility and reactivity.
  • Biological Activity: Compounds with similar frameworks have been studied for their pharmacological properties, including antitumor, antimicrobial, and neuroprotective effects. This makes them of particular interest in medicinal chemistry.
  • Synthetic Challenges: Synthesizing such complex molecules can be challenging but offers an excellent opportunity for chemists to develop innovative strategies in organic synthesis, including the use of multi-step reactions and catalysts.
  • Potential Applications: Research into dibenzoquinoline derivatives suggests possible applications in drug development, particularly in the fields of oncology and neurobiology.
  • Research Opportunities: The compound's unique properties invite further investigation, motivating budding chemists to explore its reactivity and potential uses in various fields of chemistry.

In summary, (6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol is more than just a chemical entity; it embodies a myriad of possibilities waiting to be uncovered in the realms of organic synthesis and medicinal research. As researchers continue to delve into its properties, who knows what new discoveries may emerge?

Synonyms
Lauroscholtzine
N-Methyllaurotetanine
2169-44-0
Rogersine
Boldine 2-methyl ether
2-O-METHYLBOLDINE
NSC 247564
(+)-N-Methyllaurotetanine
11558LRZ50
NSC 247506
NSC-247506
NSC-247564
1,2,10-Trimethoxy-6a-alpha-aporphin-9-ol
LAUROTETANINE, N-METHYL-
UNII-11558LRZ50
DTXSID60176073
6a-alpha-APORPHIN-9-OL, 1,2,10-TRIMETHOXY-
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S)-
DTXCID4098564
1,2,10-TRIMETHOXY-6Aalpha-APORPHIN-9-OL
CHEMBL464099
4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
Laurotetanine, N-methyl derivative of
(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol
(S)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol
N-methylaurotetanine
1,2,10-Trimethoxy-6a-.alpha.-aporphin-9-ol
N-Methyllaurotetanine; NSC 247506; NSC 247564
(+)-N-methyl-laurotetanine
GTPL13242
HY-N3398
BDBM50250422
NSC247506
NSC247564
NSC785189
AKOS032948666
FS-9571
NSC-785189
DA-74910
CS-0024109
AE-508/21133014
AE-508/21133015
AE-508/21133016
1,2,10-TRIMETHOXY-6A.ALPHA.-APORPHIN-9-OL
Q27251258