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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
633-65-8
IUPAC name
(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride
State
State

At room temperature, berberine chloride is in a solid state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.36g/mol
Molar mass
336.3620g/mol
Density
1.3000g/cm3
Appearence

Berberine chloride typically presents as a bright yellow crystalline powder. The compound is intensely colored, which is characteristic of many alkaloids.

Comment on solubility

Solubility of (6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride

The solubility of (6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride can be influenced by various factors such as its molecular structure and the presence of specific functional groups.

Key points regarding its solubility include:

  • Polar Nature: The presence of multiple methoxy (-OCH3) groups contributes to the polar characteristics of the compound, which generally enhances its solubility in polar solvents.
  • Chloride Ion: As it exists as a chloride salt, this can increase overall solubility in ionic solutions, aiding in its dissociation and dispersion in aqueous environments.
  • Hydrophilicity vs. Hydrophobicity: The balance between the hydrophilic methoxy groups and the hydrophobic, larger structural components may lead to variable solubility profiles across different solvents.

In summary, while the compound shows enhanced solubility due to its ionic nature and polar groups, the intricate structure may still present challenges in completely dissolving in non-polar solvents. Thus, it's essential to consider the solvent's polarity when attempting to dissolve this compound.

Interesting facts

Interesting Facts about (6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride

This compound, known for its complex structure and versatility, belongs to a fascinating class of organic compounds that feature intricate fused ring systems. Here are some intriguing aspects:

  • Structural Complexity: The presence of multiple methoxy groups along with a tetrahydro structure demonstrates a unique configuration that is often studied for its electronic properties and potential interactions in biological systems.
  • Role in Chemistry: Compounds like this one are often used as intermediates in organic synthesis, highlighting their importance in drug development and materials science.
  • Biological Activity: There is growing interest in how such aromatic compounds interact with biological molecules, making them potential candidates for pharmacological applications, including anti-cancer properties.
  • Diversity of Applications: Owing to their unique properties, similar compounds have found uses in developing organic light-emitting diodes (OLEDs), dyes, and even as catalysts in various chemical reactions.

As scientists continue to explore the vastness of organic chemistry, compounds like (6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride become pivotal in advancing our understanding of molecular interactions and the development of new materials.

“Chemistry is the only subject that makes you feel like a magician!” This compound certainly echoes the art of chemistry, showcasing how intricate designs yield powerful functionalities.

Synonyms
Glaucine hydrochloride
2269-06-9
(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium;chloride
69444SR62I
EINECS 218-869-1
d-Glaucine hydrochloride
1,2,9,10-Tetramethoxy-6a-alpha-aporphine hydrochloride
UNII-69444SR62I
6a-alpha-APORPHINE, 1,2,9,10-TETRAMETHOXY-, HYDROCHLORIDE
(S)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinolinium chloride
NS00083511