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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
633-65-8
IUPAC name
(6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride
State
State

At room temperature, Berberine chloride is a solid. It generally exists as a crystalline powder that is bright yellow in color.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
361.00
Boiling point (Kelvin)
634.15
General information
Molecular weight
371.82g/mol
Molar mass
371.8220g/mol
Density
1.3800g/cm3
Appearence

The appearance of Berberine chloride is a yellow to orange crystalline powder. It is often encountered in the form of a yellow solid that has a distinctive bitter taste when dissolved in water.

Comment on solubility

Solubility of (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride

The solubility of the compound (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride can be influenced by several factors. Understanding its solubility characteristics is crucial for applications in pharmaceuticals, materials science, and chemical research. Here are some essential points regarding its solubility:

  • Solvent Interaction: The presence of functional groups such as methoxy and diol suggests that the compound may exhibit different solubility behaviors in polar and non-polar solvents.
  • Chloride Ion: As a chloride salt, the ionic nature may enhance its solubility in water compared to non-ionized forms, potentially leading to increased dissolution rates.
  • Polarity: The balance of hydrophobic and hydrophilic regions within the molecular structure will significantly affect its solubility profile.
  • Temperature Dependency: Like many organic compounds, the solubility will likely vary with temperature, often increasing as the temperature rises.

In summary, while specific solubility data for this compound may not be widely available, it can be generally inferred that its solubility will be appreciably affected by the aforementioned factors. Understanding these effects is essential for optimizing its use in various applications.

Interesting facts

Interesting Facts about (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride

This compound, a member of the dibenzoquinoline family, showcases intriguing structural characteristics and potential applications in various fields of chemistry and pharmacology. Below are some fascinating aspects of this compound:

  • Hybrid Structure: The compound's structure features a complex arrangement of fused ring systems, which is characteristic of quinoline derivatives. This unique fusion confers specific electronic properties that make it interesting for medicinal chemistry research.
  • Potential Bioactivity: Many quinoline derivatives have been studied for their biological activity, including anti-cancer, anti-microbial, and anti-inflammatory properties. Research into this compound could reveal promising therapeutic avenues.
  • Intriguing Symmetry: The asymmetric centers in the molecule contribute to its chirality, which can significantly influence its biological interactions. This aspect is crucial, as enantiomers can exhibit vastly different pharmacological profiles.
  • Applications in Synthesis: The functional groups present allow for various modifications, making it a valuable intermediate in organic synthesis. Scientists can explore diverse synthetic routes to derive related compounds with tailored properties.
  • Stability Considerations: Understanding the stability of this compound under different conditions provides insight into its potential storage and handling in laboratory and industrial settings.

In summary, (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride is not just a fascinating chemical entity but also serves as a gateway to exploring the rich chemistry associated with quinoline derivatives. Its unique structure and potential for bioactivity present exciting opportunities for future research.

Synonyms
Magnoflorine, chloride
Magnoflorine chloride
6681-18-1
Escholine chloride
(+)-Magnoflorine (chloride)
(6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-1,11-diol;chloride
NSC150443
Thalictrine chloride
Corytuberine methochloride
NSC 150443
Magnoflorine-chloride
6a-alpha-APORPHINIUM, 1,11-DIHYDROXY-2,10-DIMETHOXY-6-METHYL-, CHLORIDE
CHEMBL496685
HY-N0535R
HY-N0535
BDBM50480258
AKOS030530373
CCG-268382
NSC-150443
(+)-Magnoflorine (chloride) (Standard)
AC-34442
MS-26159
CS-0009068
Magnoflorine (chloride);-Magnoflorine (chloride);Thalictrine (chloride)