Sanguinarine | Solubility of Things

Identification

Molecular formula

C₂₀H₁₄NO₄

CAS number

2447-54-3

IUPAC name

(6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

State

At room temperature, sanguinarine is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)

176.50

Melting point (Kelvin)

449.70

Boiling point (Celsius)

488.10

Boiling point (Kelvin)

761.30

General information

Molecular weight

332.33g/mol

Molar mass

332.3610g/mol

Density

1.2723g/cm³

Appearence

Sanguinarine appears as a crystalline solid with a bright orange-red color.

Comment on solubility

Solubility of (6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

The solubility of compounds can often be influenced by their molecular structure and functional groups. In the case of (6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, the following aspects of solubility should be considered:

Polarity: The presence of hydroxyl groups (-OH) typically enhances solubility in polar solvents, potentially making this compound more soluble in aqueous solutions.
Functional Group Effects: The allylic chain may impart some degree of hydrophobic character, which could affect solubility depending on the solvent environment.
Steric Factors: The bulky dibenzo structure may also contribute to solubility challenges in certain solvents, emphasizing the need for empirical testing.

Furthermore, one might find that:

Solubility could vary significantly between polar and non-polar solvents.
As a general trend, compounds like this can show better solubility in alcohols or dimethyl sulfoxide (DMSO) compared to hexane or other non-polar solvents.

In conclusion, to determine the solubility of (6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol in various solvents, experimental data will provide the most reliable information, as theoretical predictions can sometimes fall short due to the complexity of molecular interactions.

Interesting facts

Interesting Facts About (6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

(6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol is a fascinating organic compound with a unique chemical structure that warrants attention from both chemists and pharmacologists. Here are some intriguing aspects of this compound:

Structural Complexity: The compound features a complex polycyclic structure, integrating multiple fused aromatic rings. This complexity often correlates with unique biological activities and potential therapeutic uses.
Potential Biological Activities: Compounds of this class may exhibit a variety of biological properties, making them targets for drug development. Research suggests they could be investigated for their potential anti-cancer, anti-inflammatory, or neuroprotective effects.
Chirality: The specific stereochemistry, particularly the (6aS) configuration, plays a crucial role in the biological activity of the compound. Chirality can significantly affect how a compound interacts with biological systems, leading to varying efficacy and safety profiles.
Source of Inspiration: The synthesis of this compound can draw inspiration from natural products, often leading to the development of novel pharmaceuticals. Studying such compounds helps in understanding complex biochemical pathways.
Research Relevance: As scientists continue to explore and characterize this compound, its role in medicinal chemistry may bring forth new avenues for treating various conditions, particularly in the realm of cancer therapeutics.

In summary, (6aS)-6-allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol stands as a compelling example of the intricate relationship between chemical structure and biological function. Researchers are keen to delve deeper into its properties to unlock its full potential.

Synonyms

CHEMBL319557

NCGC00015297-01

Lopac-D-042

Oprea1_184185

BDBM50007424

(S)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol