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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
(6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one
State
State

At room temperature, methadone is typically a solid substance.

Melting point (Celsius)
235.90
Melting point (Kelvin)
509.05
Boiling point (Celsius)
145.00
Boiling point (Kelvin)
418.15
General information
Molecular weight
309.45g/mol
Molar mass
309.4470g/mol
Density
0.9780g/cm3
Appearence

Methadone is typically found in the form of colorless crystals, but it can also appear as a white powder. In solution, it is usually clear and colorless.

Comment on solubility

Solubility of (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one

The solubility of (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one, a complex organic compound, is intriguing and can be influenced by various factors. Here are some key points to consider about its solubility:

  • Solvent Type: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, and acetone due to the presence of the dimethylamino group, which enhances interactions with polar solvents.
  • Temperature Influence: Generally, increased temperature may improve solubility for many organic compounds, and it is expected that raising the temperature could further enhance the solubility of this compound in organic solvents.
  • pH Sensitivity: The solubility might also be affected by the pH of the solution. In more acidic or basic conditions, the dimethylamino group can either be protonated or deprotonated, changing its interaction with the solvent.
  • Concentration Effects: At higher concentrations, solubility may exhibit non-ideal behavior due to intermolecular interactions that can lead to precipitation or reduced solubility.

In summary, understanding the solubility of (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one is essential for its applications in various chemical processes and formulations. Research into specific solvent interactions and environmental conditions can provide deeper insights into its solubility behavior.

Interesting facts

Interesting Facts about (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one

(6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one is a notable compound in the field of organic chemistry, particularly due to its unique structural characteristics and potential applications. Here are some fascinating insights about this compound:

  • Synthetic Pathways: This compound is often synthesized through multi-step reactions involving ketones and amines, showcasing the complexity and versatility of organic synthesis techniques.
  • Pharmacological Potential: Compounds with similar structures have been examined for various biological activities. They may exhibit properties such as analgesic or anti-inflammatory effects, making them of interest in medicinal chemistry.
  • Structural Isomerism: The presence of chirality in (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one opens up a discussion about stereoisomers and their significance in pharmacodynamics, emphasizing how slight variations in molecular structure can dramatically impact function.
  • Application in Drug Development: With ongoing research into drug design, this compound could serve as a lead compound, inspiring modifications that enhance effectiveness or reduce side effects in therapeutic applications.
  • Notable Derivatives: Exploring its derivatives can reveal a range of biological activities and provide insights into structure-activity relationships (SAR), which is a crucial aspect of developing new pharmaceuticals.

In summary, (6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one is an intriguing compound that not only provides insights into synthetic organic chemistry but also presents potential avenues for research in pharmacology and medicinal applications. As research continues, there may be even more discoveries that enhance our understanding of its properties and uses.

Synonyms
Levomethadone
l-Methadone
Levothyl
(-)-Methadone
l-Polamivet
(R)-Methadone
(6R)-Methadone
125-58-6
Levometadona
Levadone
D-(-)-Methadone
Levomethadonum
R-(-)-Methadone
Levomethadone [INN]
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
METHADONE, L-
Levometadona [INN-Spanish]
Levomethadonum [INN-Latin]
6Y75Z4E8NS
Levomethadone (INN)
L-6-(Dimethylamino)-4,4-diphenyl-3-heptanone
(R)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone
BRN 3213668
(-)-(R)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone
LEVOMETHADONE [WHO-DD]
CHEBI:136003
DTXSID701016376
(R)-6-(Dimethylamino)-4,4-diphenyl-3-hetpanone
3-14-00-00278 (Beilstein Handbook Reference)
(6R)-6-(dimethylamino)-4,4-diphenyl-3-heptanone
3-heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6R)-
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (R)-
3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, L-
Levometadona (INN-Spanish)
Levomethadonum (INN-Latin)
(6R)-6-dimethylamino-4,4-di(phenyl)heptan-3-one
3-Hetpanone, 6-(dimethylamino)-4,4-diphenyl-, (R)-
HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, L-
R-methadone
(R)-(-)-methadone
N07BC05
DTXCID301474556
3-Hetpanone, 6-(dimethylamino)-4,4-diphenyl-, (R)-(9CI)
603-081-6
Polamivet
L-Polamidon
UNII-6Y75Z4E8NS
(-)-(R)-Methadone
BIDD:PXR0190
SCHEMBL147864
CHEMBL159659
GTPL1605
BDBM50223633
PDSP1_000586
PDSP2_000583
DB13515
NS00117935
D08121
A838934
(6R)-6-(dimethylamino)-4,4-diphenyl-heptan-3-one
Q6535776
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, L- (8CI)
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6R)- (9CI)
3-Hetpanone, 6-(dimethylamino)-4,4-diphenyl-, (R)- (9CI)