Skip to main content

Cefepime

ADVERTISEMENT
Identification
Molecular formula
C19H24N6O5S2
CAS number
88040-23-7
IUPAC name
(6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, Cefepime is a solid powder, which is usually reconstituted with a solvent to form an injectable solution for medical use.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
480.58g/mol
Molar mass
480.5750g/mol
Density
1.6700g/cm3
Appearence

Cefepime is typically a pale yellow to yellow crystalline powder. It is usually supplied as a powder that requires reconstitution into a solution for injection.

Comment on solubility

Solubility Characteristics of (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C19H24N6O5S2) is a crucial aspect of its chemical behavior, influencing both its application and efficacy. Given its complex structure, we can analyze its solubility in terms of a few key factors:

  • Polarity: The presence of functional groups such as carboxylic acids and pyridinium suggests that this compound exhibits moderate to high polarity, which can enhance its solubility in polar solvents like water.
  • Steric hindrance: The bicyclic structure may introduce steric factors that could restrict solubility in certain organic solvents, though this can vary.
  • Hydrogen bonding: The ability to form hydrogen bonds due to the carboxylic acid group can facilitate interactions with solvent molecules, promoting solubility.
  • Temperature dependence: It's important to note that solubility may vary with temperature; generally, increased temperatures lead to enhanced solubility in polar solvents.

In summary, while comprehensive data specific to this compound's solubility may be limited, its structural features suggest a potential for reasonable solubility in aqueous environments, particularly when influenced by factors such as pH and temperature. Further experimental validation is essential for a complete understanding.

Interesting facts

Interesting Facts about (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This fascinating compound, known for its intricate structure and diverse functionalities, presents a wealth of intriguing properties that merit exploration. Here are some notable aspects:

  • Bioactive Potential: The compound has shown promise in various biological applications, particularly in the realm of antibiotic research and development. Its complex framework may contribute to its effectiveness against specific bacterial strains.
  • Structural Diversity: The presence of a thiazolidine ring along with the bicyclic core makes the compound unique. This distinctive structure can lead to unique reactivity patterns that are particularly exciting for chemists.
  • Targeted Drug Design: The integration of a pyridine moiety and thienyl group opens up avenues for targeted drug design, allowing scientists to tailor its pharmacodynamic properties.
  • Intermolecular Interactions: The functional groups in this compound facilitate interesting intermolecular interactions, making it a subject of interest for studies in supramolecular chemistry.
  • Mechanisms of Action: Understanding how this compound interacts with biological systems can provide insights into its mechanism of action, leading to potential advancements in medicinal chemistry.

In summary, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid represents a significant chemical entity worthy of thorough investigation. Its intricate design not only showcases the art of chemical synthesis but also highlights the importance of novel compounds in the search for innovative therapeutic solutions.

Synonyms
DTXSID90894793
13057-93-7
PD194047
NS00069084
Pyridinium, 1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, (6R-trans)-