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S-14671

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Identification
Molecular formula
C11H13ClN2S
CAS number
69049-86-3
IUPAC name
(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole;hydrochloride
State
State

This compound is typically in a solid state at room temperature, available in crystalline or powder form.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
264.81g/mol
Molar mass
264.8100g/mol
Density
1.1600g/cm3
Appearence

The compound typically appears as a white to off-white powder or crystalline solid. It is generally available as a hydrochloride salt, which may impart its white coloring.

Comment on solubility

Solubility of (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride

The solubility of the compound (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride is an important aspect to consider when exploring its applications and behavior in various environments. This compound is typically characterized by its properties in different solvents. Here are some key points about its solubility:

  • Water Solubility: As a hydrochloride salt, it is generally more soluble in water compared to its neutral form. This increased solubility is due to the ionic nature of the hydrochloride, which interacts favorably with water molecules.
  • Organic Solvents: Solubility in organic solvents may be moderate, depending on the specific structure and functional groups present. Exploring solvents such as ethanol or methanol may yield varying results.
  • Temperature Dependence: Like many compounds, the solubility of this hydrochloride can vary with temperature. Typically, an increase in temperature can enhance solubility.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution, as changes can affect the ionization state of the compound, thus impacting its solubility profile.

Understanding these factors is crucial for applications in pharmaceuticals and materials science, where solubility can directly impact efficacy and formulation strategies. In conclusion, the solubility of (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride presents both challenges and opportunities, and thorough investigation into its solubility characteristics will provide greater insights into its potential uses.

Interesting facts

Interesting Facts about (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; hydrochloride

(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; hydrochloride is a compound that has garnered significant attention in the field of medicinal chemistry. It belongs to the class of imidazothiazoles, which are known for their diverse biological activities and potential therapeutic applications.

Biological Activity

This compound is particularly noted for its:

  • Antimicrobial properties: Research reveals its potential effectiveness against various pathogens, making it a candidate for further development in combating infections.
  • CNS effects: Its inclusion in studies has explored its impact on the central nervous system, hinting at possible applications in the treatment of neurological disorders.
  • Anti-inflammatory effects: Preliminary investigations suggest it may exhibit anti-inflammatory properties, which could be beneficial in treating conditions characterized by chronic inflammation.

Synthetic Pathways

The synthesis of this compound is intricate and showcases the versatility of organic chemistry. The key steps generally involve:

  • Formation of the imidazole ring: A crucial process that defines the biochemical properties of the entire molecule.
  • Thiazole integration: The incorporation of the thiazole moiety adds essential biological functionality.

Applications in Research

Pharmaceutical companies and academic institutions are keenly researching compounds like (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole for their potential in drug development. As stated by a recent study, "the exploration of imidazothiazole derivatives could lead to groundbreaking advancements in modern medicine."

In conclusion, (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; hydrochloride is a fascinating compound with promising therapeutic avenues that merit further exploration in the scientific community.

Synonyms
Levamisole hydrochloride
16595-80-5
Levamisole HCl
Ergamisol
Ascaridil
Tramisol
Decaris
Levasole
Solaskil
NSC-177023
Spartakon l
L-narpenol
R 12,564
L-Tetramisole hydrochloride
R 12564
DTXSID7047518
Tetramisole hydrochloride, (s)-
Levamisoli hydrochloridum
DL9055K809
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-
DTXCID5027518
R 12654
R-12564
NSC177023
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (6S)-
Ergamisole
Immunol
Trimisol
LevaMed
Tramisol Gel
Ripercol L
PROHIBIT
Cloridrato de Levamizol
Hydrochloride, Levamisole
LevaMed Soluble Pig Wormer
Levasole Soluble Pig Wormer
Levasole Cattle Wormer Bolus
LevaMed Soluble Drench Powder
Prohibit Soluble Drench Powder
Ripercol L Soluble Drench Powder
ICI-59623
RP-20605
Ripercol L Bolus, Tramisol Cattle Wormer Bolus
Ripercol L, Tramisol Soluble Drench Powder for Sheep
Ripercol L Wormer Oblets, Tramisol Sheep Wormer Oblets
Levasole Sheep Wormer Bolus, Tramisole Sheep Wormer Oblets Tablets
(S)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole Monohydrochloride
240-654-6
Levamisole Soluble Drench Powder, Levasole, Levasole Soluble Drench Powder, Tramisol Soluble Drench Powder
(S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride
Levamisol hydrochloride
Tramisole
Niratic hydrochloride
Stimamizol hydrochloride
Niratic-puron hydrochloride
Levamisole (hydrochloride)
MFCD00012675
R-12,564
CHEBI:6433
(-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride
Dekaris
Levacide
Levadin
Nemicide
Meglum
Nilverm forte
Worm-chek
(6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
Ripercol-L
Citarin L
16595-80-5 (HCL)
Levomysol hydrochloride
(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride
(S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride
L(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
KW 2LE-T
SMR001230807
KW-2-LE-T
Levamisole hydrochloride [USAN]
Levamisole Hydrochloride (1.0 mg/mL in Methanol)
SR-01000075969
EINECS 240-654-6
74191-78-9
(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Hydrochloride
UNII-DL9055K809
LEV hydrochloride
Ergamisol (TN)
NCGC00094446-03
Prestwick_294
Levamisole hydrochloride [USAN:USP]
(7S)-7-phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene hydrochloride
Levamisole HCl(Ergamisol)
L-(-)-2,3,5,6-Tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride
Ergamisol (TN) (Janssen)
CAS-16595-80-5
CHEMBL1770
SCHEMBL19226
BMK1-H6
Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride
MLS002153440
MLS002222198
MLS002695941
orb134393
SPECTRUM1503245
Levamisole hydrochloride (USP)
MSK5587A
((-)-Tetramisole hydrochloride
HMS1568F05
HMS1922M11
BCP13755
Levamisole Hydrochloride (Ergamisol)
Tox21_111282
Tox21_500690
CCG-40301
HY-13666R
LEVAMISOLE HYDROCHLORIDE [MI]
s1939
Levamisole HCl - Bio-X trade mark
LEVAMISOLE HYDROCHLORIDE [JAN]
AKOS015951350
Levamisole (hydrochloride) (Standard)
Tox21_111282_1
FL29670
KW-2299
LP00690
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-
LEVAMISOLE HYDROCHLORIDE [MART.]
LEVAMISOLE HYDROCHLORIDE [USP-RS]
LEVAMISOLE HYDROCHLORIDE [WHO-DD]
LEVAMISOLE HYDROCHLORIDE [WHO-IP]
NCGC00094046-01
NCGC00261375-01
NCGC00263461-01
AC-23973
AS-13370
BL166245
HY-13666
EU-0100690
L0231
LEVAMISOLE HYDROCHLORIDE [GREEN BOOK]
NS00076395
T1215
(-)-Tetramisole hydrochloride, >=99% (GC)
LEVAMISOLE HYDROCHLORIDE [ORANGE BOOK]
C07906
D00750
D78137
EN300-122366
L 9756
LEVAMISOLE HYDROCHLORIDE [EP MONOGRAPH]
LEVAMISOLE HYDROCHLORIDE [USP MONOGRAPH]
LEVAMISOLI HYDROCHLORIDUM [WHO-IP LATIN]
SR-01000075969-1
SR-01000075969-6
Levamisol hydrochloride 100 microg/mL in Acetonitrile
Q27107205
Z1550648764
Levamisol hydrochloride, VETRANAL(TM), analytical standard
Levamisole Hydrochloride 1.0 mg/ml in Methanol (as free base)
Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-
Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-
(-)-2,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride
(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole;hydrochloride
(S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazolehydrochloride
Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-
Levamisole hydrochloride, European Pharmacopoeia (EP) Reference Standard
Levamisole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Levamisole hydrochloride, United States Pharmacopeia (USP) Reference Standard
Levamisole hydrochloride for system suitability, European Pharmacopoeia (EP) Reference Standard