Interesting facts
Exploring the Unique Properties of (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
This compound represents a fascinating and complex molecule, celebrated for its intricate structural features and diverse biological activities. As we delve into the details, here are some interesting aspects worth noting:
- Structural Complexity: The compound features multiple chiral centers and a unique cyclopenta[a]phenanthrene framework, making it a valuable subject for stereochemical studies.
- Biological Significance: Compounds of this nature often exhibit significant pharmacological properties. This specific compound has been explored for its potential roles in hormonal modulation and anti-cancer activities.
- Hydroxyl Functional Groups: The presence of hydroxyl (-OH) groups in its structure enhances its reactivity and solubility, which can be particularly beneficial for biological interactions.
- Synthetic Challenge: The synthesis of such complex molecules is a testament to advanced synthetic organic chemistry techniques, often involving multi-step processes and careful chiral resolution.
- Research Implications: The study of this compound can pave the way for the development of novel therapeutic agents, leading to advancements in medical chemistry and pharmacology.
In summary, the rich structural and functional attributes of this compound make it an intriguing subject for chemists and researchers alike. Understanding its properties not only contributes to chemical knowledge but also holds promise for future innovations in drug development and therapeutic interventions.
Synonyms
methylprednisolone
83-43-2
Medrol
Metilprednisolone
Medrone
6alpha-Methylprednisolone
Metilbetasone
Medrate
Urbason
Dopomedrol
Medesone
Mesopren
Metastab
Metrisone
Noretona
Promacortine
Urbasone
Besonia
Moderin
Solomet
Wyacort
Methylprednisolon
Sieropresol
Suprametil
Esametone
Firmacort
Medixon
Metrocort
Metysolon
Nirypan
Reactenol
Lemod
Artisone-wyeth
Medrol dosepak
Methyleneprednisolone
Metilprednisolona
Medrol adt pak
Predni N Tablinen
6-alpha-Methylprednisolone
delta(1)-6alpha-Methylhydrocortisone
NSC-19987
1-Dehydro-6alpha-methylhydrocortisone
Methylprednisolonum
Metilprednisolone [DCIT]
Summicort
Prednisolone, methyl-
Methylprednisolonum [INN-Latin]
Metilprednisolona [INN-Spanish]
6-methyl-prednisolone
Prednisolone, 6alpha-methyl-
CHEBI:6888
HSDB 3127
EINECS 201-476-4
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
UNII-X4W7ZR7023
BRN 2340300
DTXSID7023300
delta(sup 1)-6-alpha-Methylhydrocortisone
U-67,590A
X4W7ZR7023
U 7532
6alpha-methyl prednisolone
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
J3.872E
Methylprednisolone, 6-alpha
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
Methylprednisolone (Standard)
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
MLS000028541
MLS001148159
DTXCID903300
EC 201-476-4
4-08-00-03498 (Beilstein Handbook Reference)
NSC19987
MEPRDL
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Medlone 21
Methylprednisolone [USP:INN:BAN:JAN]
Metipred
SMR000058330
Summicort;
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
NEO-MEDROL COMPONENT METHYLPREDNISOLONE
Prednol- L
Methylprednisolonum (INN-Latin)
Metilprednisolona (INN-Spanish)
Depo-Medrol (acetate)
METHYLPREDNISOLONE (MART.)
METHYLPREDNISOLONE [MART.]
METHYLPREDNISOLONE (USP-RS)
METHYLPREDNISOLONE [USP-RS]
CAS-83-43-2
Methylprednisolone (USP:INN:BAN:JAN)
METHYLPREDNISOLONE (EP MONOGRAPH)
METHYLPREDNISOLONE [EP MONOGRAPH]
6?-Methyl Prednisolone
METHYLPREDNISOLONE (USP MONOGRAPH)
METHYLPREDNISOLONE [USP MONOGRAPH]
6 Methylprednisolone
MLS002638721
Prednisolone, 6.alpha.-methyl-
Solpredone
Duralone
Meprolone
Prednilen
Radilem
DepMedalone
Methylprednisole
Medrol Tablets
Veriderm Medrol
Caberdelta M
Depo Moderin
Depo-Nisolone
Methylpred DP
Mega-Star
Prednol-L
Predni-M-Tablinen
.DELTA.1-6.alpha.-Methylhydrocortisone
NCGC00016330-01
Prestwick_622
Medrol (TN)
MFCD00010591
Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6alpha,11beta)-
Metilbetasone Solubile
6-|A-Methylprednisolone
Methylprednisolene Tablets
Opera_ID_1576
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl-
CHEMBL650
Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6a,11b)-
6-alpha-methyl prednisolone
6.alpha.-Methylprednisolone
SCHEMBL5084
BSPBio_000158
MLS002207191
SPBio_002377
METHYLPREDNISOLONE [MI]
BPBio1_000174
GTPL7088
METHYLPREDNISOLONE [INN]
METHYLPREDNISOLONE [JAN]
HY-B0260R
METHYLPREDNISOLONE [HSDB]
METHYLPREDNISOLONE [VANDF]
HMS1568H20
HMS2090B13
HMS2095H20
HMS2230D16
HMS3259J04
HMS3712H20
6alpha-Methylprednisolone, >=98%
METHYLPREDNISOLONE [WHO-DD]
HY-B0260
Tox21_110376
Tox21_302018
BDBM50103616
LMST02030178
Methylprednisolone (JP17/USP/INN)
s1733
AKOS015969744
Pregna-1,4-diene-3,20-dione, 6-alpha-methyl-11-beta-17,21-trihydroxy-
Tox21_110376_1
CCG-220279
DB00959
FM25546
KS-1273
METHYLPREDNISOLONE [GREEN BOOK]
NC00691
METHYLPREDNISOLONE [ORANGE BOOK]
NCGC00022735-03
NCGC00022735-06
NCGC00255269-01
NCI60_001657
CS-0694768
M1665
NS00000345
C16437
D00407
EN300-7414014
METHYLPREDNISOLONE COMPONENT OF NEO-MEDROL
Q417222
SR-01000003089
SR-01000003089-2
BRD-K35240538-001-03-1
BRD-K35240538-001-11-4
BRD-K35240538-001-26-2
6-alpha-Methylprednisolone 100 microg/mL in Acetonitrile
METHYLPREDNISOLONE ACETATE IMPURITY B [EP IMPURITY]
6alpha-Methylprednisolone, VETRANAL(TM), analytical standard
1,4-pregnadien-6alpha-methyl-11beta, 17, 21-triol-3, 20-dione
11beta,17,21-trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
Methylprednisolone, British Pharmacopoeia (BP) Reference Standard
Methylprednisolone, European Pharmacopoeia (EP) Reference Standard
Pregna-1,20-dione, 11.beta.,17,21-trihydroxy-6.alpha.-methyl-
Pregna-1,20-dione, 6.alpha.-methyl-11.beta.-17,21-trihydroxy-
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
METHYLPREDNISOLONE HYDROGEN SUCCINATE IMPURITY A [EP IMPURITY]
Methylprednisolone, United States Pharmacopeia (USP) Reference Standard
Methylprednisolone for system suitability A, EuropePharmacopoeia (EP) Reference Standard
Methylprednisolone, Pharmaceutical Secondary Standard; Certified Reference Material
Pregna-1,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)-
Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6I+/-,11I(2))-
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;Medrone;Medrol;6a-Methylprednisolone
201-476-4
Solubility of (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
The solubility of the compound (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one plays a crucial role in its potential applications and biological activities. Understanding solubility can shed light on various properties including:
When discussing this particular compound, it is important to consider:
In general, compounds with multiple -OH groups demonstrate enhanced solubility in aqueous solutions, while those rich in hydrocarbon chains might show increased affinity for organic solvents. Therefore, specific solubility tests in different solvents are essential to accurately characterize this compound's behavior.
As a result, the solubility profile of this compound can provide insights into its efficacy for research and development in pharmaceutical formulations and other applications.