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Nandrolone (Deca-Durabolin)

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Identification
Molecular formula
C18H26O2
CAS number
434-22-0
IUPAC name
7-(1-hydroxy-1-methyl-prop-2-ynyl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one
State
State

Nandrolone is at room temperature a solid compound, usually found in a powder form before being formulated into a solution for injectable administration.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
586.00
Boiling point (Kelvin)
859.15
General information
Molecular weight
274.41g/mol
Molar mass
274.4060g/mol
Density
1.1253g/cm3
Appearence

Nandrolone appears as a white or almost white crystalline powder. It is odorless and light-sensitive. It is typically available in a micronized form for enhanced solubility and absorption in the body when used in pharmaceutical applications.

Comment on solubility

Solubility of 7-(1-hydroxy-1-methyl-prop-2-ynyl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one

The solubility of 7-(1-hydroxy-1-methyl-prop-2-ynyl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one is a complex topic due to the compound's unique structural characteristics. Factors influencing its solubility include:

  • Polarity: The presence of the hydroxyl group contributes to polar interactions, which can enhance solubility in polar solvents such as water.
  • Hydrophobic regions: The extensive hydrocarbon framework may render the compound more soluble in non-polar solvents, such as hexane or toluene.
  • Temperature: Solubility can significantly change with temperature; typically, solubility increases with higher temperatures for many organic compounds.

In summary, the solubility of this compound can be predicted to exhibit:

  1. Higher solubility in polar solvents due to the hydroxyl group.
  2. Increased solubility in non-polar solvents arising from the large hydrophobic decahydro-phenanthrene structure.
  3. Variation with temperature, which should be considered in practical applications.

It is important to conduct experimental solubility tests in defined conditions to ascertain the precise solubility profile of this compound, as theoretical predictions can only provide an initial understanding.

Interesting facts

Interesting Facts about 7-(1-hydroxy-1-methyl-prop-2-ynyl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one

This intriguing compound is part of the phenanthrene family and possesses several noteworthy features that make it an interesting subject for study in both organic chemistry and pharmaceuticals. Below are some fascinating aspects:

  • Structural Complexity: The molecule exhibits a unique multi-ring structure that contributes to its diverse reactivity and stability. The presence of a decahydrophenanthrene framework allows for intriguing interactions with various biological systems.
  • Functional Groups: The inclusion of a hydroxyl group and a propyne side chain enhances the compound's solubility and reactivity, enabling it to participate in a variety of chemical reactions. This positioning can lead to the synthesis of analogs with desirable pharmacological properties.
  • Biological Relevance: Compounds like this one are often studied for their potential biological activities. Many phenanthrene derivatives have been noted for various biological activities, including anti-inflammatory and anticancer effects, prompting a surge of research in related compounds.
  • Nature's Inspiration: The complexity and variety of this compound echo the remarkable chemistry found in nature, particularly in natural products derived from plants and fungi, which often serve as starting points for drug development.

As you delve deeper into the world of organic compounds, consider the implications of synthetic modifications to this compound, as it may pave the way for innovative therapeutic solutions. The structural versatility of compounds like 7-(1-hydroxy-1-methyl-prop-2-ynyl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one exemplifies how a single molecule can lead to numerous exciting avenues of research.

Synonyms
R1O6MXI51T
UNII-R1O6MXI51T
RO-5-2537
4,4a,4b,5,6,7,8,8a,9,10-Decahydro-7-(1-hydroxy-1-methyl-2-propyn-1-yl)-2(3H)-phenanthrenone
605-57-2
2(3H)-Phenanthrenone, 4,4a,4b,5,6,7,8,8a,9,10-decahydro-7-(1-hydroxy-1-methyl-2-propyn-1-yl)-
SCHEMBL30291864
DTXSID10274937
7-(2-hydroxybut-3-yn-2-yl)-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-phenanthren-2-one
23294-32-8