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Prostaglandin E2

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Identification
Molecular formula
C20H32O5
CAS number
363-24-6
IUPAC name
7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid
State
State

At room temperature, Prostaglandin E2 is a viscous liquid, though it can be crystalline if prepared under certain conditions.

Melting point (Celsius)
-6.00
Melting point (Kelvin)
267.15
Boiling point (Celsius)
422.10
Boiling point (Kelvin)
695.25
General information
Molecular weight
352.47g/mol
Molar mass
352.4650g/mol
Density
1.0545g/cm3
Appearence

Prostaglandin E2 appears as a colorless to pale yellow viscous liquid, often containing a slight turbidity due to its hygroscopic nature. It can also form crystalline solid compounds under certain conditions, especially when fully purified.

Comment on solubility

Solubility of 7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid

The solubility of 7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid can be quite intriguing due to its complex structure. This compound consists of various functional groups that influence its solubility in different solvents. Here are some key points to consider:

  • Polarity: Given the presence of hydroxyl (-OH) groups, the molecule exhibits a degree of polarity. This enhances its solubility in polar solvents such as water.
  • Hydrophobic regions: However, the long hydrophobic carbon chain may lead to lower solubility in highly polar media and increased solubility in non-polar solvents.
  • pH dependence: The carboxylic acid functional group can ionize depending on the pH of the solvent, which can significantly affect solubility. It is more soluble in alkaline conditions compared to acidic ones.

In summary, the solubility of this compound is influenced by the balance between its polar and non-polar characteristics, making it crucial to consider the solvent environment when assessing its behavior. As noted, it may exhibit variable solubility based on these factors.

Interesting facts

Interesting Facts about 7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid

This compound is a fascinating example within the realm of organic chemistry, exhibiting complex structural arrangements that exemplify the diversity of chemical compounds. Here are some intriguing aspects:

  • Chirality: The presence of chirality in the molecule, indicated by the (1R,2S) specification, means it can exist in multiple stereoisomeric forms. Chirality is essential in the biological activity of compounds as often, only one enantiomer is active in biological systems.
  • Synthesis: Synthesizing complex compounds like this can reveal important techniques and strategies in organic synthesis, such as the application of asymmetric synthesis, which allows for the selective formation of one enantiomer over another.
  • Natural Occurrence: Compounds similar to this one may have roles in nature, potentially serving as biosynthetic intermediates or even bioactive agents. Understanding their pathways can lead to new insights in drug discovery and medicinal chemistry.
  • Functional Groups: This compound contains several functional groups, including ketones and hydroxyls, that can lead to various chemical reactions. These functional groups impact solubility, reactivity, and interaction with other molecules, making them vital points of study.
  • Potential Applications: The structural elements present in this compound could hint at its potential uses in pharmaceuticals, materials science, or food chemistry, showcasing the interdisciplinary nature of studying such compounds.

As we delve deeper into the complexity of this compound, we uncover not just its individual characteristics, but also how it fits into broader chemical narratives and its potential impacts on various scientific fields. Each study of a compound like 7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid invites further inquiry and inspires new questions regarding its synthesis and applications.

Synonyms
7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-1-cyclopent-3-enyl]heptanoic acid
7-[(1R,2S)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid
CHEMBL1084644
CBiol_001911
KBioGR_000178
KBioSS_000178
SCHEMBL6417551
CHEBI:92069
KBio2_000178
KBio2_002746
KBio2_005314
KBio3_000355
KBio3_000356
Bio1_000197
Bio1_000686
Bio1_001175
Bio2_000178
Bio2_000658
BDBM50318491
AKOS030241098
PD195409
Q27163864
7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-enyl)heptanoic acid