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Cefepime

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Identification
Molecular formula
C19H24N6O5S2
CAS number
88040-23-7
IUPAC name
7-[[2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methyl-ethoxy)imino-acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State
At room temperature, cefepime is in a solid state, typically provided as a powder for reconstitution in clinical settings.
Melting point (Celsius)
74.00
Melting point (Kelvin)
347.00
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.00
General information
Molecular weight
480.57g/mol
Molar mass
480.5730g/mol
Density
1.6300g/cm3
Appearence
Cefepime is a pale yellow powder.
Comment on solubility

Solubility Characteristics

The solubility of the compound 7-[[2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methyl-ethoxy)imino-acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C19H24N6O5S2) can be influenced by various factors:

  • Polar Structure: The presence of multiple functional groups, such as carboxylic acids and amine groups, suggests a potential for enhanced solubility in polar solvents like water.
  • Hydrophilic Groups: The carboxy (-COOH) and amino (-NH2) groups are known for their ability to form hydrogen bonds with water, thereby increasing solubility.
  • Ionization: Given the presence of the pyridin-1-ium group, the compound may exhibit ionization properties in aqueous solutions, further affecting its solubility profile.
  • Molecular Interactions: The interaction with solvents can vary, as both hydrophilic and potentially lipophilic characteristics exist within the molecule.

In conclusion, while the specific solubility data for this compound may not be readily available, its diverse functional groups strongly suggest it is likely to have a reasonable solubility in water, with the potential for variable behavior in non-polar solvents. Understanding these attributes is crucial for applications in pharmaceutical formulations and biological interactions.

Interesting facts

Interesting Facts about 7-[[2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methyl-ethoxy)imino-acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This complex compound boasts significant relevance in the field of medicinal chemistry, particularly due to its potential applications in combating bacterial infections. Here are some fascinating aspects surrounding this intriguing molecule:

  • Structure Diversity: The intricate structure includes various functional groups, such as thiazole, pyridine, and carboxylic acid moieties. This diversity allows for unique pharmacological interactions within biological systems.
  • Antimicrobial Potential: Studies suggest that compounds featuring a thiazole ring often exhibit antibacterial properties, making this compound a candidate for drug development aimed at treating resistant strains of bacteria.
  • Mechanism of Action: Understanding how this compound interacts with bacterial targets can lead to insights into new antibiotic mechanisms. It may inhibit critical bacterial enzymes or disrupt essential cellular processes.
  • Drug Design: The design of this compound illustrates the process of analog development, where modifications of existing molecules lead to enhanced efficacy and reduced toxicity.
  • Multi-target Interactions: With its multiple functional groups, this compound can potentially interact with several biological targets simultaneously—an attractive feature for polypharmacology.

In conclusion, the exploration of such compounds exemplifies the excitement of discovery in medicinal chemistry. As scientists continue to study their characteristics and interactions, the hope is to uncover novel therapies to address urgent health challenges. As one researcher aptly put it, "Every molecule tells a story; we just need to listen."