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Rosuvastatin

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Identification
Molecular formula
C22H28FN3O6S
CAS number
147098-20-2
IUPAC name
7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoic acid
State
State

At room temperature, Rosuvastatin is a solid; it is usually available in tablet form for pharmaceutical use.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
403.60
Boiling point (Kelvin)
676.75
General information
Molecular weight
500.62g/mol
Molar mass
500.6180g/mol
Density
1.1498g/cm3
Appearence

Rosuvastatin is typically found as a white to off-white powder. Its physical appearance can vary slightly depending on the specific form or salts used in medication formulations.

Comment on solubility

Solubility of 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoic acid

The solubility of the compound C22H28FN3O6S is influenced by various factors that stem from its complex molecular structure. Understanding its solubility is key to anticipating its behavior in biological and environmental systems. Here are some essential points to consider:

  • Polarity: The presence of multiple hydroxyl (–OH) groups tends to enhance the polarity of the compound, which generally promotes solubility in polar solvents such as water.
  • Functional Groups: Functional groups like chlorophenoxy and hydroxy moieties can form hydrogen bonds, further affecting solubility characteristics.
  • Hydrophobic Regions: The hydrophobic cyclopentyl and but-1-enyl groups, however, might lead to decreased solubility in water, suggesting that this compound could exhibit a moderate solubility profile.
  • Saturation: The extent of saturation in its structure may influence the ability of the compound to interact with solvent molecules, as saturated compounds typically exhibit distinct solubility trends.

Ultimately, while the presence of hydrophilic functional groups hints at reasonable solubility in aqueous solutions, the competing hydrophobic characteristics suggest a complexity in dissolving behavior that may lead to varied solubility depending on environmental conditions.

Interesting facts

Interesting Facts about 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoic acid

This complex compound boasts a diverse structure and intriguing properties, making it a fascinating subject of study in the field of chemistry. Here are some key points to note:

  • Pharmaceutical Relevance: The compound is related to a class of molecules that have garnered interest for their potential therapeutic applications, particularly in the treatment of various diseases.
  • Functional Groups: Its structure contains multiple functional groups, including hydroxy (-OH) and carboxylic acid (-COOH), which play critical roles in biological activity and solubility.
  • Stereochemistry: The specific arrangement of atoms can lead to different stereoisomers, which can profoundly affect the compound’s biological properties and interactions.
  • Biological Activity: Compounds similar to this one have been shown to exhibit strong biological activities, such as anti-inflammatory and anti-cancer effects, making them of great interest to medicinal chemists.
  • Research Applications: The compound can serve as a lead compound for drug development, providing a scaffold for the design of more potent and selective derivatives.

As a scientist or chemistry student, exploring the properties and potential applications of 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoic acid can open doors to innovative research and advancements in pharmaceuticals.

In the words of a renowned chemist, "Every complex molecule hides a story waiting to be unveiled."

Synonyms
D-Cloprostenol
(+)-5-trans Cloprostenol
7-[2-[4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
57968-81-7
40665-92-7
40665-93-8
72029-43-7
(-)-Cloprostenol
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5E)-rel-
16-(3-chlorophenoxy)-17,18,19,20-tetranorprostaglandin F2 alpha
SCHEMBL14913507
DTXSID60274386
HMS3749A13
(Z)-7-[(1R,2R,3S,5S)-2-[(E)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
BCP18137
GIA55598
rel-(E)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid
rel-(Z)-7-((1R,2R,3R,5S)-2-((S,E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoic acid
7-{2-[4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoic acid
NS00096443
15S-Cloprostenol pound>>(+)-15-Epi-Cloprostenol
206555-98-8