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Cefepime

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Identification
Molecular formula
C19H24N6O5S2
CAS number
88040-23-7
IUPAC name
7-[[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino-acetyl]amino]-3-(imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, cefepime is typically a solid in the form of a powder. It is used mainly in clinical settings in its reconstituted form for intravenous or intramuscular injection.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
480.57g/mol
Molar mass
480.5710g/mol
Density
1.8913g/cm3
Appearence

Cefepime is generally observed as a white to pale yellow or yellow powder. It is highly crystalline and is used primarily in its hydrochloride form for pharmaceutical applications.

Comment on solubility

Solubility of C19H24N6O5S2

The solubility of the compound 7-[[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino-acetyl]amino]-3-(imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid can be understood through several key factors:

  • Polarity: The presence of polar functional groups such as carboxylic acid and amino groups can enhance the solubility in polar solvents like water.
  • Intermolecular Interactions: Hydrogen bonding may contribute significantly to solubility, particularly in aqueous solutions.
  • pH Dependence: The solubility may vary with pH, especially for acidic or basic moieties that can become ionized.
  • Saturation Limits: The compound’s solubility can be limited by its molecular structure and size, affecting its ability to dissolve efficiently.

In general, complex organic compounds like this may exhibit variable solubility depending on the solvent, with potential solubility challenges in non-polar solvents. Experimentation under specific conditions is often required to ascertain precise solubility data.

Interesting facts

Interesting Facts About 7-[[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino-acetyl]amino]-3-(imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound represents a unique intersection of organic chemistry and medicinal applications, showcasing the intricate design of molecular structures aimed at addressing specific biological interactions.

Key Features:

  • Diverse Functional Groups: The compound possesses a variety of functional groups, such as thiadiazole and imidazopyridazine, which can influence its reactivity and interactions with biological targets.
  • Potential Therapeutic Uses: Due to its complex structure, this compound may exhibit potential as a pharmaceutical agent, possibly in the realms of anti-infective or anticancer therapies.
  • Design of Targeted Agents: The careful arrangement of its components reflects a deliberate attempt to target specific biological pathways, making it a subjects of interest in drug design.
  • Research Contributions: Scientists are actively researching the implications of this compound in various sectors of biochemistry, particularly related to its mechanism of action and efficacy.

As the fields of medicinal chemistry and pharmacology continue to evolve, compounds like this are vital for understanding how complex molecular architectures can be harnessed for therapeutic benefit. The exploration of 7-[[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino-acetyl]amino]-3-(imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid not only enriches our knowledge in chemical synthesis but also opens up new horizons for drug discovery and development.

Synonyms
DTXSID50861224
1-({7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl}methyl)imidazo[1,2-b]pyridazin-1-ium