Skip to main content

Cefaclor

ADVERTISEMENT
Identification
Molecular formula
C15H14ClN3O4
CAS number
53994-73-3
IUPAC name
7-[(2-amino-2-phenyl-acetyl)amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, cefaclor is typically found in a solid state, often formulated into oral tablets or capsules for administration.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
368.28g/mol
Molar mass
368.2750g/mol
Density
1.5200g/cm3
Appearence

Cefaclor appears as a white to off-white crystalline powder. It is practically odorless and has a slight bitter taste. The powder is hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 7-[(2-amino-2-phenyl-acetyl)amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound C15H14ClN3O4, commonly known as 7-[(2-amino-2-phenyl-acetyl)amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, can be influenced by various factors including its molecular structure and the presence of functional groups. Below are some primary aspects regarding its solubility:

  • Polarity: The presence of polar functional groups such as carboxylic acid and amino groups likely increases the compound’s solubility in polar solvents, particularly water.
  • Solvent Compatibility: This compound may display variable solubility when dissolved in common solvents like:
    • Highly polar solvents (e.g., water) - expected greater solubility.
    • Less polar or non-polar solvents (e.g., hexane) - expected reduced solubility.
  • pH Influence: Being a carboxylic acid, the solubility will also depend on the pH of the solution. At higher pH values, the deprotonation of the carboxylic group could enhance aqueous solubility.
  • Temperature Effects: Increased temperature can often lead to higher solubility for many compounds, although this can vary depending on the specific interactions of the functional groups.

In conclusion, while the precise solubility data may necessitate empirical measurements, understanding the chemical structure provides valuable insight into potential solubility behaviors. As a rule of thumb, "like dissolves like," meaning that polar compounds tend to dissolve well in polar solvents while non-polar compounds do so in non-polar solvents.

Interesting facts

Exploring 7-[(2-amino-2-phenyl-acetyl)amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This intriguing compound belongs to a class of molecules that often exhibit significant biological activity, making it an interesting subject of study for chemists and biochemists alike. With its unique structure characterized by a bicyclic framework, it presents opportunities for various applications in medicinal chemistry.

Key Features

  • Mechanism of Action: Compounds like this one can interact with biological macromolecules, potentially inhibiting specific enzymes or pathways. This suggests that it could play a role in drug design targeted at various diseases.
  • Synthetic Pathways: The synthesis of such compounds often involves multi-step processes that showcase the ingenuity of organic synthesis. Not only does this require careful consideration of reaction conditions, but it also highlights the importance of understanding mechanisms of reactions.
  • Structure-Activity Relationship (SAR): The specific architectural features of this compound can significantly influence its biological activity. Studying variations of this compound may yield insights into which structural elements are crucial for its efficacy.
  • Research Potential: Ongoing research may explore modifications to enhance the pharmacological properties or to minimize any potential toxicity, which is fundamental in the development of new therapeutic agents.

As a chemistry student, one might appreciate the profound implications that such compounds have on the development of new pharmaceuticals. This particular structure could serve as a case study for understanding how small changes in the molecular design can lead to significant differences in biological activity.

In summary, 7-[(2-amino-2-phenyl-acetyl)amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is not just a complex chemical entity but a potential key that could unlock the door to novel therapeutic solutions. Its study encapsulates the challenges and excitement inherent in chemical research.

Synonyms
Loribid
760915-44-4
KT 3777; LY 163892; Lorabid
SCHEMBL1819705
DTXSID70860991
SR-01000944481
SR-01000944481-1
7-[2-Amino(phenyl)acetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid