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Cefmetazole

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Identification
Molecular formula
C15H17N7O5S2
CAS number
56796-30-4
IUPAC name
7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, Cefmetazole is in a solid state, existing as a crystalline powder. It is characterized by its stability under standard conditions and should be stored in a cool, dry place away from light to prevent degradation.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
472.45g/mol
Molar mass
472.4470g/mol
Density
1.7800g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It is almost odorless.

Comment on solubility

Solubility of 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound with the chemical formula C15H17N7O5S2 can be influenced by several factors, leading to fascinating implications for its applications:

  • Ionic nature: The presence of multiple functional groups, including two carboxylic acid groups, suggests that this compound may exhibit good solubility in polar solvents, particularly water.
  • Dipole interactions: The hydroxyl and carboxylic acid functionalities can engage in hydrogen bonding, enhancing its solubility further in polar environments.
  • Hydrophobic segments: The methoxy and hydrophobic sections might restrict solubility in non-polar solvents, indicating a potential amphiphilic character when in mixed solvent systems.

In practical terms, it can be expected that:

  • The compound may dissolve readily in aqueous solutions during pharmaceutical formulations.
  • Its solubility could be affected by pH, with higher solubility in more alkaline conditions due to deprotonation of carboxylic acid groups.
  • Comparatively low solubility in organic solvents may limit its applications in those areas.

In summary, the solubility profile of this compound is characterized by its polar functionalities that favor solubility in aqueous environments, while its hydrophobic parts may create challenges in organic solvents. Understanding these aspects is crucial for effective utilization in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound is a fascinating member of the chemical world, characterized by its intricate structure and potential applications. Here are some noteworthy aspects:

  • Complex Structure: The compound features a bicyclic framework, a unique feature that contributes to its biological activity and interaction with biological macromolecules.
  • Pharmacological Potential: Compounds with similar structural motifs have shown a variety of pharmacological activities, making them of interest in medicinal chemistry. Researchers are keen on exploring their roles in drug design and discovery.
  • Functional Groups: The presence of carboxylic acid groups and hydroxyphenyl moieties adds to its lipophilicity, which may enhance membrane permeability and promote stronger binding interactions in biological systems.
  • Synthesis Relevance: The synthesis of this compound can involve advanced organic reactions, providing an excellent study topic for students and professionals interested in synthetic organic chemistry.
  • Interdisciplinary Appeal: Given its complexity, this compound serves as an excellent example for discussions in various chemical disciplines, including organic synthesis, medicinal chemistry, and even pharmacology.

In conclusion, 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is not just a compound but a significant subject of investigation that can inspire future research and collaboration across various fields of science.

Synonyms
latamoxef (stereochemistry undefined)
78997-87-2
SCHEMBL49016
DTXSID60860804
AKOS025311559
Q13020344
7-[2-Carboxy(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid