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Theophylline

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Identification
Molecular formula
C7H8N4O2
CAS number
58-55-9
IUPAC name
7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione
State
State

In its pure form, theophylline is typically found as a solid at room temperature.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
180.16g/mol
Molar mass
180.1640g/mol
Density
1.1580g/cm3
Appearence

Theophylline is a white, crystalline powder. It is odorless, and has a bitter taste.

Comment on solubility

Solubility of 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione

The solubility of 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione is a fascinating topic due to its unique structure and properties. This compound is likely to exhibit varying solubility based on a few key factors:

  • Polarity: Given the presence of the diethylamino group, which enhances solubility in polar solvents, this compound may show better solubility in aqueous solutions.
  • pH Sensitivity: The solubility can also be influenced by the pH of the solution. In more alkaline conditions, the ionization of functional groups may increase solubility.
  • Solvent Type: Non-polar solvents may not dissolve this compound effectively, demonstrating the importance of choosing the right solvent.

To illustrate its behavior:

  • Highly soluble: Typically in polar solvents such as water or methanol.
  • Limited solubility: Often observed in non-polar solvents like hexane or toluene.

In conclusion, understanding the solubility profile of 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione is critical for its applications in various formulations, and it emphasizes the importance of solvent selection in chemical processes.

Interesting facts

Interesting Facts About 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione

The compound 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione is a fascinating member of the purine family, known for its structural complexity and biological significance. Here are some intriguing aspects to consider:

  • Pharmacological Relevance: This compound is often studied for its role as a potential therapeutic agent, particularly in the field of pharmacology, where it may exhibit stimulant properties similar to caffeine.
  • Bioactivity: Compounds in this class have been observed to interact with various biological targets, including adenine receptors, which can influence cellular signaling pathways.
  • Synthetic Pathways: The synthesis of this compound incorporates various organic reactions, including alkylation and amination, making it a valuable model for teaching synthetic organic chemistry.
  • Structural Characteristics: The diethylamino group in this compound provides unique electron-donating characteristics, enhancing its reactivity and solubility, which are important for its biological activity.
  • Research Applications: Scientists are investigating the use of this compound in areas such as neurology and cardiology, where its effects on the central nervous system and heart function are of particular interest.

In summary, 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione exemplifies the intersection of chemistry and biology. Its complex structure and potential applications make it a compelling topic of study for both chemists and biologists alike. As research progresses, we may uncover even more about its properties and potential uses in medicine.

Synonyms
Etamiphylline
Etamiphyllin
Camphophyline
Millophylline
314-35-2
Etamifilina
Etamifillina
Etamiphyllinum
NSC-38348
221A91BQ2S
7-(beta-Diethylaminoethyl)theophylline
ethamicyclin
7-[2-(diethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
etamiphyllin monohydrochloride
7-(2-(diethylamino)ethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
R03DA06
206-244-6
Etaminophylline
Milliphylline
Parephyllin
Solufilina
Soluphyline
Corafil
Queryl
Diethylaminoethyltheophylline
Dietamiphylline
Millophyline
Milheparin
Diaethylaminoaethyl-theophyllin
7-(Diethylaminoethyl)theophylline
Etamiphyllin heparinate
7-(2-(Diethylamino)ethyl)theophylline
7-(2-Diethylaminoethyl)theophylline
NSC 38348
R-3588
1,3-Dimethyl-7-(2-(diethylamino)ethyl)xanthine
7-(2-(Diethylamino)ethyl)-1,3-dimethylxanthine
Diethylaminoethyltheophylline heparinate
7-[2-(diethylamino)ethyl]-1,3-dimethylpurine-2,6-dione
Etamiphylline (INN)
1H-Purine-2,6-dione, 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl-
1H-Purine-2,6-dione, 7-[2-(diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-
ETAMIPHYLLINE [INN]
7-[2-(Diethylamino)ethyl]-1,3-dimethylxanthine
59547-58-9
Etamiphyllin [INN]
Etamifillina [DCIT]
7-[2-(Diethylamino)ethyl]theophylline
Etamifilina [INN-Spanish]
Etamiphylline [INN-French]
Etamiphyllinum [INN-Latin]
Diethylaminoethyl theophylline
Theophylline, 7-(2-(diethylamino)ethyl)-
Theophylline, 7-[2-(diethylamino)ethyl]-
1,3-Dimethyl-7-[2-(diethylamino)ethyl]xanthine
EINECS 206-244-6
BRN 0291098
Diaethylaminoaethyl-theophyllin [German]
UNII-221A91BQ2S
Theophylline, 7-(2-diethylamino)ethyl-
ETAMIPHYLLIN [MI]
4-26-00-02409 (Beilstein Handbook Reference)
ETAMIPHYLLIN [WHO-DD]
SCHEMBL355304
F3229-0069
CHEMBL2104264
BDBM82014
DTXSID10861866
CHEBI:135157
AAA31435
NSC38348
7-[(Diethylamino)ethyl]theophylline
NSC_28329
7-[2-(Diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
AKOS024481061
{7-[(Diethylamino)ethyl]theophylline}
DB13592
Diaethylaminoaethyl-theophyllin(GERMAN)
7-(2-(Diethylamino)ethyl)-Theophylline
{7-[2-(Diethylamino)ethyl]theophylline}
CAS_314-35-2
HY-105762
NS00008740
Theophylline, {7-[2-(diethylamino)ethyl]-}
VU0606073-1
D07378
Q5402412
{7-[2-(Diethylamino)ethyl]-1,} 3-dimethylxanthine
1, {3-Dimethyl-7-[2-(diethylamino)ethyl]xanthine}
1H-Purine-2, 7-[2-(diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-
7-(2-(diethylamino)ethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione #