Skip to main content

Theophylline hydrate

ADVERTISEMENT
Identification
Molecular formula
C9H14N4O2
CAS number
58-55-9
IUPAC name
7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione;hydrochloride
State
State

In standard room temperature conditions, theophylline hydrate is in a solid state. It is usually stored in its crystalline form.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.15
Boiling point (Celsius)
560.20
Boiling point (Kelvin)
833.35
General information
Molecular weight
180.16g/mol
Molar mass
198.2160g/mol
Density
1.1900g/cm3
Appearence

Theophylline hydrate is typically in the form of a white crystalline powder or colorless crystals. It has a slightly bitter taste. When exposed to moisture, it may form hydrate crystals.

Comment on solubility

Solubility of 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione; hydrochloride

The solubility of the compound 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione hydrochloride is an important aspect to consider for its applications and effectiveness in various formulations. Typically, this compound is characterized by the following solubility features:

  • High Solubility in Water: Being a hydrochloride salt, it tends to exhibit good solubility in aqueous solutions, which is essential for pharmacological applications.
  • Influence of pH: The solubility can vary significantly with changes in pH. In acidic environments, the compound may remain in its soluble form more effectively.
  • Solvent Polarity: Organic solvents may influence the solubility; however, it is primarily more soluble in polar solvents due to its ionic nature.

It is critical to note that the solubility characteristics can also affect the bioavailability and pharmacodynamics of the compound, making it essential for researchers to evaluate the solubility under specific conditions. As stated, "the greater the solubility, the more successful the formulation" in terms of therapeutic efficacy.

In conclusion, understanding the solubility of 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione hydrochloride is vital not only for its practical applications but also for optimizing its use in various chemical and biological systems.

Interesting facts

Interesting Facts about 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione; hydrochloride

This compound is a fascinating member of the purine family known for its biological activity, particularly as a pharmacological agent. Here are some engaging aspects of its importance and characteristics:

  • Pharmacological Applications: Often used in research as a stimulant, this compound has effects on muscle relaxation and vasodilation. It can be crucial in the study of cardiovascular health and various diseases.
  • Structural Complexity: The presence of both diethylamino and dimethyl groups in its structure gives rise to interesting variations in its chemical behavior and interactions. This complexity enhances its pharmacological profile, making it a subject of investigation in medicinal chemistry.
  • Mechanism of Action: As a purine derivative, this compound engages with various receptors and pathways in the body, contributing to its stimulating effects. Understanding its mechanism can provide insights into developing new therapeutic agents.
  • Research Context: This compound is often used in neuropharmacological studies to explore its impact on neurotransmitter systems, making it invaluable for students and professionals in neuroscience.
  • Historical Significance: The exploration of compounds like this one paved the way for many modern pharmaceuticals, highlighting the iterative nature of drug discovery and development.

In summary, 7-[2-(diethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione; hydrochloride is not only a key player in biochemistry but also serves as a reminder of the intricate relationship between chemical structure and biological function. As researchers continue to investigate its properties and effects, the potential applications of this compound are vast and promising.

Synonyms
Etamiphyllin hydrochloride
17140-68-0
Etamiphylline hydrochloride
Etamiphyllin HCl
7-(2-(DIETHYLAMINO)ETHYL)THEOPHYLLINE HYDROCHLORIDE
66ZCZ8Z4HE
7-[2-(diethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione hydrochloride
1H-Purine-2,6-dione, 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl-, hydrochloride
7-[2-(diethylamino)ethyl]-1,3-dimethylpurine-2,6-dione;hydrochloride
7-(2-(Diethylamino)ethyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione hydrochloride
EINECS 241-204-1
UNII-66ZCZ8Z4HE
Solufilina (TN)
Chlorhydrate de diethylaminoethyltheophylline [French]
7-(2-(N,N-Diethylamino)ethyl)theophylline hydrochloride
7-(beta-Diaethylamino-aethyl)-theophyllin-hydrochlorid [German]
Chlorhydrate de diethylaminoethyltheophylline
7-(beta-Diaethylamino-aethyl)-theophyllin-hydrochlorid
Theophylline, 7-(2-(diethylamino)ethyl)-, hydrochloride
DTXSID40169089
WZNIVRAEOQQUIB-UHFFFAOYSA-N
SAA14068
AKOS030228401
ETAMIPHYLLIN HYDROCHLORIDE [MI]
AS-68659
ETAMIPHYLLIN HYDROCHLORIDE [WHO-DD]
7-(2-(Diethylamino)ethyl)theophylline HCl
NS00087132
A11483
D07923
7-DIETHYLAMINOETHYL THEOOHYLLINE HYDROCHLORIDE
7-DIETHYLAMINOETHYL THEOPHYLLINE HYDROCHLORIDE
Q27264042