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Cefotetan

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Identification
Molecular formula
C17H17N7O8S4F2
CAS number
69712-56-7
IUPAC name
7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, Cefotetan is in a solid state, typically in crystalline powder form. It is stable under normal conditions.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
596.60g/mol
Molar mass
596.6000g/mol
Density
0.8000g/cm3
Appearence

Cefotetan appears as a white to off-white crystalline powder. It is often supplied as a salt for stability and solubility purposes.

Comment on solubility

Solubility of 7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C17H17N7O8S4F2)

The solubility of complex organic compounds, like the one mentioned above, can often be quite intricate and dependent on several factors. Here are some key points to consider:

  • Water Solubility: This compound contains multiple polar functional groups, such as carboxylic acid and hydroxyl (-OH) groups, which may enhance its solubility in water. However, the presence of hydrophobic components could limit this solubility.
  • Solvent Specificity: The solubility of the compound may vary significantly with different solvents. For instance, it might dissolve more readily in organic solvents like DMSO or ethanol compared to water.
  • Temperature Influence: Increasing temperature may increase solubility, particularly for crystalline forms of the compound.
  • pH Sensitivity: The solubility in aqueous solutions could be highly sensitive to pH, as the ionization of the carboxylic acid group can affect overall solubility.

"Solubility is not just a chemical property; it is governed by the interactions and balance between different functional groups in a compound."

In conclusion, while it is possible that this compound exhibits moderate solubility in polar solvents, the overall behavior is likely to be complex and would require experimental characterization under various conditions for a definitive understanding.

Interesting facts

Interesting Facts about 7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This fascinating compound is a member of a diverse class of biochemicals known for their unique structural features and potential biological applications. Here are some intriguing aspects of this compound:

  • Innovative Design: The intricate structure combines multiple functional groups, which enhances its reactivity and potential interaction with biological target sites.
  • Multi-Target Potential: The presence of various moieties suggests that it may possess the ability to interact with multiple biological pathways, making it a subject of interest for drug development and therapeutic research.
  • Unique Sulfur Chemistry: The compound incorporates sulfur atoms in its structure, specifically in the form of both sulfonyl and thiol functionalities. This can influence both its biological activity and reactivity, offering unique pathways for synthesizing derivatives.
  • Tetrazole Ring: The inclusion of a tetrazole ring adds notable pharmacological properties. Tetrazoles are often used in pharmaceuticals for their ability to enhance the bioactivity of various compounds.

As scientists continue to explore the potential uses of this compound, it contributes valuable insights into the field of medicinal chemistry and drug design. The blend of thiol and acetamido groups enhances its biochemical versatility, indicating that it could play a significant role in developing new therapies. As the saying goes in the world of chemistry, "A single atom can change everything," and in this case, the careful arrangement and choice of atoms present in this compound may lead to groundbreaking discoveries.


The ongoing research into this compound not only sheds light on its immediate applications but also expands our understanding of how complex molecular architectures can be utilized to drive innovative solutions in science and medicine.

Synonyms
DTXSID00861158
5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, (6R,7R)-
Flomoxef Sodium - Bio-X trade mark
FF41634
BF300080
7-{2-[(Difluoromethyl)sulfanyl]acetamido}-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid