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Theophylline

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Identification
Molecular formula
C7H8N4O2
CAS number
58-55-9
IUPAC name
7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione
State
State

At room temperature, theophylline is typically in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
180.16g/mol
Molar mass
180.1640g/mol
Density
1.3000g/cm3
Appearence

Theophylline typically appears as a white crystalline powder. It is practically odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione

The solubility of 7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione can vary significantly depending on various factors. Here are some key points to consider:

  • Polarity: This compound contains both polar (e.g., -NH2 and -OH groups) and non-polar regions. This polarity plays a crucial role in its solubility in different solvents.
  • Solvent Interaction: It tends to be more soluble in polar solvents such as water and alcohol, while its solubility decreases in non-polar solvents like hexane.
  • Temperature: Higher temperatures generally increase solubility. As the temperature rises, molecules move more rapidly, allowing for better interactions with the solvent.
  • pH Level: The solubility can also be influenced by the pH of the solution. For instance, at lower pH levels, the compound may ionize, enhancing its solubility in aqueous solutions.

In summary, the solubility of 7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione is dynamic, influenced by its interplay with the solvent's properties, and can vary significantly with changing environmental conditions. Understanding these factors is crucial when working with this compound in laboratory and industrial applications.

Interesting facts

Interesting Facts about 7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione

This compound, often known for its stimulating properties, plays a crucial role in various areas of research and application. Here are some noteworthy points:

  • Bioactivity: The compound is a known methylxanthine, a class of molecules that includes caffeine. It's recognized for its ability to act as a stimulant, increasing alertness and reducing the perception of fatigue.
  • Pharmacological Applications: While primarily studied for its impact on the central nervous system, this compound has been investigated for its potential therapeutic effects in treating conditions such as asthma and cardiovascular diseases.
  • Metabolic Pathways: Upon ingestion, the compound is metabolized in the liver, where it competes with other xanthines and interacts with adenosine receptors, elucidating its mechanism of action.
  • Synthetic Variations: Scientists have developed several analogs and derivatives of this compound to enhance its pharmacological properties and develop new drugs.
  • Research Significance: The compound is widely utilized in various biochemical studies, particularly those exploring the modulation of neurotransmitters and the effects of stimulants on cognitive functions.
  • Interesting Trivia: The compound's structure reflects its intricate design, showcasing the significance of the purine backbone, which is fundamental to many biological molecules, particularly nucleotides and nucleic acids.

In conclusion, the study of 7-[2-(dimethylamino)ethyl]-1,3-dimethyl-purine-2,6-dione goes beyond its chemical characteristics, opening avenues in pharmacology, biochemistry, and neuroscience. As noted by researchers, "Understanding the properties of such compounds not only enhances our knowledge of biological systems but also paves the way for innovative therapeutic strategies." This compound certainly holds a prominent place in the realm of chemical research.

Synonyms
DIMETHAZAN
519-30-2
Dimethazan [INN]
7-[2-(dimethylamino)ethyl]-1,3-dimethylpurine-2,6-dione
H943V308AD
7-(2-Dimethylaminoethyl)theophylline
Dimethazanum
Dimetazano
Dimetazano [INN-Spanish]
Dimethazanum [INN-Latin]
Dimetazan
UNII-H943V308AD
EINECS 208-266-1
7-[2-(dimethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
DIMETHAZAN [MI]
Oprea1_473124
SCHEMBL49056
CHEMBL1739955
DTXSID10199858
CHEBI:135024
7-(2-Dimethylaminoethyl)-1,3-dimethyl-2,6(1H,3H)-purindion
STK677633
1,2,3,6-Tetrahydro-1,3-dimethyl-7-(2-dimethylaminoethyl)-2,6-purindion
1,3-Dimethyl-7-(2-dimethylaminoeethyl)-2,6-dioxo-1,2,3,6-tetrahydropurin
7-(2-Dimethylaminoethyl)-1,3-dimethyl-2,6(1H,3H)-purindion [IUPAC]
AKOS001680195
CCG-115533
NCGC00245876-01
NS00043623
Q5277304
3,7-Dihydropurine-2,6-dione, 7-(2-dimethylaminoethyl)-1,3-dimethyl-
7-[2-(dimethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione