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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2F
CAS number
63527-52-6
IUPAC name
7-[[2-(fluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

Cefotaxime is typically in a solid state at room temperature, occurring as a powder form. It is often used in pharmaceutical formulations where it may be reconstituted for injection.

Melting point (Celsius)
88.50
Melting point (Kelvin)
361.65
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
455.45g/mol
Molar mass
455.4480g/mol
Density
1.5500g/cm3
Appearence

Cefotaxime is a white to off-white crystalline powder. It is hygroscopic and should be protected from light. The compound may appear as a solid powder in its pure form or as granular particles.

Comment on solubility

Solubility of 7-[[2-(fluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of chemical compounds can provide insight into their potential applications and behavior in various environments. For the compound C16H17N5O7S2F, it presents an interesting case due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple functional groups (such as amino, carboxylic acid, and hydroxyl) suggests that the compound is likely to be polar, which typically enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to hydroxyl and carboxyl groups can contribute to increased solubility in aqueous solutions.
  • Influence of Fluorine: The fluoromethylsulfanyl group may introduce unique interactions in solution, potentially affecting the overall solubility profile. Fluorine can alter polarity and influence solvation dynamics.
  • Concentration Dependence: The solubility may vary with concentration, indicating the possibility of achieving higher solubility at elevated temperatures or in different solvent mixtures.

In summary, while the exact solubility can vary based on experimental conditions, the characteristic functional groups in this compound suggest a favorable solubility in polar solvents, which might be beneficial for pharmaceutical applications or during synthesis processes.

Interesting facts

Interesting Facts about 7-[[2-(fluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound, with its intricate structure, is an exciting subject of study due to its potential applications and unique chemical properties. Below are some intriguing aspects surrounding this remarkable molecule:

  • Diverse Functionality: The compound features multiple functional groups, including a methoxy group and a tetrazole ring, which can enhance reactivity and interactions in biological systems.
  • Potential Therapeutic Applications: Due to its complex structure, this compound may exhibit pharmacological activities, such as anti-inflammatory or antimicrobial effects, opening up pathways for medicinal applications.
  • Sulfur Chemistry: The presence of sulfur within the compound contributes to its unique properties, including potential roles in biochemistry and sustainable chemistry, reminding us that sulfur is often an overlooked element in drug design.
  • Analytical Interest: The molecule's complicated architecture presents challenges and opportunities for characterization using advanced techniques such as NMR and mass spectrometry, highlighting the importance of analytical chemistry in understanding such compounds.
  • Innovation in Synthesis: The synthesis of this compound may require innovative methods that can pave the way for new strategies in organic synthesis, encouraging chemists to explore creative approaches to construct complex molecules efficiently.

In summary, this compound not only showcases the beauty of chemical diversity but also stimulates the imagination and research of those in the scientific community. As we continue to explore such intricate structures, we are reminded of the vast possibilities and potential that chemical science holds.