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Ceftezole

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Identification
Molecular formula
C14H15N7O4S2
CAS number
23564-05-8
IUPAC name
7-[(2-hydroxy-2-phenyl-acetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, ceftezole exists as a solid. It is usually prepared as a sodium salt for pharmaceutical use, which enhances its solubility in water.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
405.44g/mol
Molar mass
391.0000g/mol
Density
1.5500g/cm3
Appearence

Ceftezole appears as a white to off-white crystalline powder. It is generally odorless and has a slightly bitter taste.

Comment on solubility

Solubility Characteristics

The solubility of the compound 7-[(2-hydroxy-2-phenyl-acetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C14H15N7O4S2) can be quite intricate to determine due to its complex structure. Here are some notable points regarding its solubility:

  • Solvent Dependency: This compound is likely to exhibit variable solubility in different solvents. Common solvents to consider include water, ethanol, and dimethyl sulfoxide (DMSO).
  • Polarity Influence: The presence of polar groups, such as carboxylic acid and hydroxyl functionalities, suggests that it may be more soluble in polar solvents compared to non-polar solvents.
  • pH Sensitivity: The acidity of the carboxylic acid group can affect solubility; at low pH, the compound may exist in a protonated form, which could alter its solubility profile.
  • Temperature Effects: Generally, solubility can also increase with temperature, so conducting experiments across a range of temperatures may yield more insights.

In conclusion, while comprehensive data on the solubility of this particular compound may be limited, understanding its structure and the influence of various factors on solubility can help in predicting its behavior in different environments. Future studies focusing on these aspects could provide valuable insights into its chemical properties.

Interesting facts

Interesting Facts about 7-[(2-hydroxy-2-phenyl-acetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This fascinating compound showcases the complexity and ingenuity of modern chemistry, particularly within the realm of medicinal chemistry. Here are some captivating facts about it:

  • Multifaceted Structure: The compound features a unique bicyclic framework, which contributes to its diverse biological activities and interactions with various enzymes.
  • Pharmacological Potential: Its intriguing design implies potential as a pharmaceutical candidate, possibly exhibiting antibacterial or anti-inflammatory properties, a focus area in drug development.
  • Functional Groups: The presence of various functional groups, such as amides and ketones, allows this compound to participate in numerous chemical reactions, enhancing its versatility.
  • Sulfur's Role: The incorporation of sulfur atoms in its structure can aid in enhancing the compound's pharmacokinetic properties, such as its absorption and metabolism.
  • Tetrazole Moiety: The inclusion of a tetrazole ring is particularly interesting, as it is known to impart stability and can influence the biological activity of compounds.

Overall, this compound illustrates the complexity of synthetic organic chemistry and its critical role in developing new therapeutic agents. Its elaborate structure serves as a reminder of how intricate relationships between chemical properties and biological activity can lead to novel drug discoveries.

Synonyms
7-{[hydroxy(phenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
1205565-14-5
Spectrum_000147
Spectrum2_001997
Spectrum3_001495
Spectrum4_000159
Spectrum5_001770
Oprea1_303696
BSPBio_003109
KBioGR_000638
KBioSS_000627
DivK1c_000197
SPBio_002213
CHEMBL173793
SCHEMBL10604265
KBio1_000197
KBio2_000627
KBio2_003195
KBio2_005763
KBio3_002609
DTXSID00860444
NINDS_000197
65338-32-1
CCG-22192
STK177294
AKOS000714959
AKOS022003332
IDI1_000197
DB-026421
BRD-A23933379-236-04-9
7-(2-HYDROXY-2-PHENYLACETAMIDO)-3-{[(1-METHYL-1H-1,2,3,4-TETRAZOL-5-YL)SULFANYL]METHYL}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid