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Aminophylline

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Identification
Molecular formula
C16H24N10O4
CAS number
317-34-0
IUPAC name
7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethyl-purine-2,6-dione
State
State
Aminophylline is typically found in a solid state at room temperature, usually in a powder form. It is used in a variety of pharmaceutical applications, requiring dissolution to use in liquid medications.
Melting point (Celsius)
241.00
Melting point (Kelvin)
514.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
420.44g/mol
Molar mass
420.4350g/mol
Density
1.3801g/cm3
Appearence

Aminophylline typically appears as a white or slightly yellow powder. It is a crystalline compound that is odorless, or it might have a slight ammonia-like odor due to its breakdown components.

Comment on solubility

Solubility of 7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethyl-purine-2,6-dione

The solubility of 7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethyl-purine-2,6-dione is influenced by several factors due to its complex molecular structure. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl groups contributes to the overall polarity of the compound, which generally enhances solubility in polar solvents such as water.
  • Hydrophilic Functional Groups: The hydroxyethyl and hydroxymethyl groups allow for hydrogen bonding with water molecules, further increasing solubility.
  • Solvent Compatibility: This compound may show varying solubility in organic solvents, largely dependent on their polar or non-polar nature. For instance, it will be more soluble in polar solvents compared to non-polar solvents.
  • Temperature Dependency: As with many compounds, solubility might increase with temperature, making it more soluble at higher temperatures.

In summary, the solubility of this compound is expected to be relatively high in aqueous solutions, particularly due to its polar characteristics and the ability to engage in hydrogen bonding. However, precise solubility values should be determined experimentally to provide definitive insights.

Interesting facts

Interesting Facts About 7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethyl-purine-2,6-dione

This compound, often referred to due to its complex structure, belongs to a class of molecules known as purine derivatives, specifically modified xanthine derivatives. It plays a significant role in many biological systems, particularly within the realm of biochemistry and pharmacology. Here are some intriguing aspects:

  • Biological Importance: Purines are fundamental to various biological processes, including the synthesis of nucleic acids, energy metabolism, and cellular signaling.
  • Pharmacological Applications: Compounds in this category can exhibit a range of biological activities. They may act as antioxidants, affect neuromodulation, or even function in the treatment of various diseases.
  • Structure-Activity Relationship: The specific arrangement of functional groups in this compound enhances its potential interaction with biological targets, making it a subject of interest for drug design and discovery.
  • Analog Development: Researchers often synthesize analogs of purine derivatives to increase efficacy, improve solubility, and reduce side effects, making this compound a pivotal model in medicinal chemistry.

As chemists and biologists continue to explore compounds like this one, they uncover novel insights into their mechanisms of action and therapeutic potential. By utilizing techniques such as spectroscopy and molecular modeling, the intricate details of such compounds can be elucidated, paving the way for advancements in medical science.

In the words of a famous chemist, "The beauty of chemistry lies in its ability to explain the complexity of the natural world." This compound exemplifies that idea, containing a rich tapestry of functional groups and interactions that capture the imagination of all who study it.

Synonyms
Xanthinol
2530-97-4
xantinol
UNII-TN1B5910V2
7-[2-hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl]-1,3-dimethylpurine-2,6-dione
TN1B5910V2
7-(2-Hydroxy-3-(N-(2-hydroxyethyl)-N-methylamino)propyl)theophylline
7-{2-hydroxy-3-[(2-hydroxyethyl)(methyl)amino]propyl}-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione
DTXSID1048255
Theophylline, 7-(2-hydroxy-3-(N-(2-hydroxyethyl)-N-methylamino)propyl)-
Xavin
Jupal
7-(2-hydroxy-3-((2-hydroxyethyl)(methyl)amino)propyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
7-{2-hydroxy-3-[(2-hydroxyethyl)(methyl)amino]propyl}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
7-(2-hydroxy-3-((2-hydroxyethyl)(methyl)amino)propyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
SCHEMBL121656
CHEMBL1624126
DTXCID6028230
CHEBI:94314
STL581678
AKOS026751462
DB09092
NS00008286
EN300-18568176
Q8042975
7-(2-Hydroxy-3-[(2-hydroxyethyl)(methyl)amino]propyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione #