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Galantamine

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Identification
Molecular formula
C17H21NO3
CAS number
357-70-0
IUPAC name
7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one
State
State

Galantamine is typically found in a solid state at room temperature. It is stable under normal conditions but should be stored in a tightly sealed container in a cool, dry place to maintain its stability and potency.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
485.50
Boiling point (Kelvin)
758.65
General information
Molecular weight
368.43g/mol
Molar mass
368.4250g/mol
Density
1.3300g/cm3
Appearence

Galantamine is a white to off-white crystalline powder. It has a characteristic crystalline structure that appears as fine needle-like formations under a microscope.

Comment on solubility

Solubility of 7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one

The solubility of complex organic compounds like 7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one can vary significantly based on several factors. Here are some considerations regarding its solubility:

  • Polarity: The presence of functional groups, such as the hydroxyl group (-OH) and methoxy groups (-OCH3), influences the polarity of the compound. Generally, increased polarity leads to improved solubility in polar solvents like water.
  • Solvent Interactions: For this compound, it may show better solubility in organic solvents such as ethanol, acetone, or DMSO, as it can interact favorably with the organic nature of these solvents.
  • pH Sensitivity: If the compound is protonated or deprotonated depending on the pH of the solution, its solubility might increase in acidic or basic environments, respectively.
  • Temperature: Typically, solubility increases with temperature for organic compounds, so heating the solvent might enhance dissolution.

In summary, while 7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one might have varying degrees of solubility based on these factors, experimental determination would be essential to obtain precise solubility data. Understanding these parameters is crucial for effectively utilizing this compound in chemical applications.

Interesting facts

Interesting Facts About 7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one

This intriguing compound belongs to a class of organic molecules characterized by complex molecular structures and diverse biological applications. Its unique structure allows it to engage in a variety of chemical interactions, making it a fascinating subject for both academic research and practical applications.

Biological Significance

  • Pharmacological Potential: The compound is found to exhibit promising pharmacological properties, making it a candidate for further investigation in the development of new medicinal therapies.
  • Antioxidant Activity: Research suggests that it may possess notable antioxidant properties, which could help in combating oxidative stress in biological systems.

Chemical Properties

One of the standout features of this compound is its rich array of functional groups which contribute to its reactivity. For instance:

  • The presence of multiple methoxy groups can enhance its solubility and reactivity with other chemical entities.
  • The hydroxyl group on the phenyl ring may play a critical role in hydrogen bonding, affecting the compound's behavior in different environments.

Cultural Relevance

Beyond its scientific applications, the compound can inspire creativity in other fields:

  • Chemical Art: Chemists and artists have explored the aesthetic aspect of molecular structures, drawing parallels between complex chemical forms and artistic designs.
  • Education: Molecules like this one can serve as excellent examples in educational settings to teach concepts such as stereochemistry and functional group analysis.

In summary, this compound exemplifies the intricate relationship between chemistry and biological function. Continued research could unveil new dimensions of its potential, contributing to advancements in medicinal chemistry and beyond.

Synonyms
7-[(2-hydroxyphenyl)methyl-methylamino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one
Speciozine
Speciosin
Speciozin
(7S)-6,7-Dihydro-7-[[(2-hydroxyphenyl)methyl]methylamino]-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H
(7S)-6,7-Dihydro-7-[[(2-hydroxyphenyl)methyl]methylamino]-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
10-{[(2-hydroxyphenyl)methyl](methyl)amino}-3,4,5,14-tetramethoxytricyclo[9.5.0.0(2),?]hexadeca-1(16),2(7),3,5,11,14-hexaen-13-one
7-[(2-hydroxybenzyl)(methyl)amino]-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one
NSC 317021
BRN 2957282
C28H31NO6
BBL034029
STL372812
AKOS025247956
Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-7-(((2-hydroxyphenyl)methyl)methylamino)-1,2,3,10-tetramethoxy-, (S)-
VS-12385
4-14-00-00941 (Beilstein Handbook Reference)
7-[(2-hydroxyphenyl)methyl-methyl-amino]-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one