Skip to main content

Acebutolol

ADVERTISEMENT
Identification
Molecular formula
C18H28N2O4
CAS number
37517-30-9
IUPAC name
7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxy-ethyl]amino]propyl]-1,3-dimethyl-purine-2,6-dione
State
State

At room temperature, Acebutolol is in a solid-state, appearing as a white crystalline powder.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
566.80
Boiling point (Kelvin)
839.90
General information
Molecular weight
336.43g/mol
Molar mass
336.3940g/mol
Density
1.2800g/cm3
Appearence

Acebutolol typically appears as a white or almost white crystalline powder. It is often odorless and may have a bitter taste.

Comment on solubility

Solubility of 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxy-ethyl]amino]propyl]-1,3-dimethyl-purine-2,6-dione

The solubility of the compound with the chemical formula C18H28N2O4 is of considerable interest in various applications, particularly in pharmaceuticals. The intricate structure of this compound, which features multiple functional groups, influences its solubility characteristics significantly. Here’s a deeper insight:

  • Hydrophilic Groups: The presence of hydroxyl (-OH) groups contributes to its hydrophilicity, allowing it to interact favorably with polar solvents, such as water.
  • Hydrophobic Regions: Conversely, the aromatic rings and the dimethyl groups introduce hydrophobic characteristics, possibly leading to lower solubility in polar environments.
  • Overall Behavior: This compound may exhibit moderate solubility in aqueous solutions, depending on pH and temperature. As “like dissolves like”, the compatibility of solubility largely hinges on the solvent used.

Therefore, understanding the balance between its hydrophilic and hydrophobic components is essential for predicting its solubility behavior in various solvents. This knowledge not only aids in formulation but also in determining bioavailability and efficacy in pharmaceutical applications.

Interesting facts

Interesting Facts about 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxy-ethyl]amino]propyl]-1,3-dimethyl-purine-2,6-dione

This compound is a fascinating example of a purine derivative that exhibits a variety of biological activities. It is noteworthy for its role in the field of medicinal chemistry, where it is studied for its potential therapeutic implications. Here are some compelling aspects associated with this compound:

  • Bioactivity: This compound has shown significant promise in modulating various biochemical pathways, primarily due to its ability to interact with adenosine receptors.
  • Antioxidant Properties: The presence of hydroxyl groups in its structure enhances its ability to scavenge free radicals, providing insight into its potential use as an antioxidant.
  • Structure-Activity Relationship: Researchers are particularly interested in how slight modifications in its structure can lead to a dramatic change in its biological activities, making it a valuable model for drug design.
  • Role in Research: It serves as a tool compound in studying cellular signaling pathways, particularly in contexts related to neurology and cardiology.
  • Synthetic Pathways: Understanding the synthetic pathways that lead to the creation of this compound offers students and researchers insights into the intricacies of organic synthesis and chemical reactions.

As emphasized by many in the field, "The intricacy of chemical compounds like this one not only deepens our knowledge of molecular interactions but also the vast potential these interactions have in therapeutic applications." This underscores the importance of interdisciplinary research combining chemistry, biology, and medicine.

Overall, the study of 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxy-ethyl]amino]propyl]-1,3-dimethyl-purine-2,6-dione not only enriches our understanding of complex organic molecules but also opens up new avenues for drug discovery and development.

Synonyms
Reproterol
54063-54-6
Reproterolum
Reproterol [INN:BAN]
Reproterolum [INN-Latin]
EINECS 258-956-1
Reproterol (INN)
D 1959
UNII-11941YC6RN
BRN 0590567
11941YC6RN
REPROTEROL [MI]
REPROTEROL [INN]
REPROTEROL [WHO-DD]
DTXSID8023553
7-(3-((beta,3,5-Trihydroxyphenethyl)amino)propyl)theophylline
D-1959
5-26-14-00026 (Beilstein Handbook Reference)
7-(3-((2-(3,5-Dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)theophylline
1,2,3,6-Tetrahydro-1,3-dimethyl-7-(3-((beta,3,5-trihydroxyphenethyl)amino)propyl)-2,6-purindion
Reproterolum (INN-Latin)
Theophylline, 7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)-
1H-Purine-2,6-dione, 7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)-3,7-dihydro-1,3-dimethyl-
7-(3-((.BETA.,3,5-TRIHYDROXYPHENETHYL)AMINO)PROPYL)THEOPHYLLINE
reproterolo
7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
7-(3-{[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino}propyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
DTXCID003553
R03AC15
R03CC14
258-956-1
7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethylpurine-2,6-dione
SCHEMBL83298
CHEMBL1095607
CHEBI:135612
WVLAAKXASPCBGT-UHFFFAOYSA-N
DB12846
DA-67158
HY-135490
CS-0113240
NS00007356
D08474
L013423
Q1292703
7-(3-{[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino}propyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione