Interesting facts
Interesting Facts about 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
This compound is a notable member of the naphthyridine family, which has gained attention for its potential therapeutic applications. Here are some fascinating aspects of this compound:
- Pharmaceutical Potential: The structural characteristics of this compound suggest it may play a role in medicinal chemistry, particularly in the development of new drugs targeting various biological pathways.
- Diverse Applications: Due to its unique functional groups, this compound could be explored for use in:
- Antiviral agents
- Antibacterial properties
- Cancer treatments
- Fluorinated Components: The presence of fluorine atoms is noteworthy. Fluorination can enhance a compound's biological activity and environmental stability, which has made these derivatives popular in drug design.
- Aminopyrrolidine Moiety: The 3-aminopyrrolidin-1-yl group contributes to the molecule's ability to interact with biological systems, potentially influencing its pharmacokinetics and pharmacodynamics.
- Structure-Activity Relationship (SAR): The unique configuration of the naphthyridine backbone integrated with difluorophenyl highlights the significance of SAR studies in optimizing lead compounds for better efficacy and selectivity.
In conclusion, this compound's intricate structure, combined with its potential therapeutic implications, makes it a compelling subject for further investigation in both academic and industrial chemistry settings. As always, the ongoing research into its properties could lead to breakthroughs that enhance our understanding of similar compounds in the field.
Synonyms
Tosufloxacin
100490-36-6
108138-46-1
tosufloxacin tosilate
Abbott 61827
Ozex
Abbott-61827
A 61827
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
A 67107
tosufloxacine
tosufloxacino
CCRIS 6304
CHEBI:77581
UNII-GHJ553KQPS
A-61827
GHJ553KQPS
Tosufloxacin [USAN:INN]
BRN 4913117
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Tosufloxacin (USAN)
TOSUFLOXACIN [MI]
TOSUFLOXACIN [INN]
TOSUFLOXACIN [USAN]
TOSUFLOXACIN [MART.]
TOSUFLOXACIN [WHO-DD]
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-
1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
DTXSID2044135
A-67107
100490-36-6 (free base)
T-3262
TOSUFLOXACIN (MART.)
T 3262
A 60969
A-64730
(+/-)-7-(3-AMINO-1-PYRROLIDINYL)-1-(2,4-DIFLUOROPHENYL)-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID
1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID, 7-(3-AMINO-1-PYRROLIDINYL)-1-(2,4-DIFLUOROPHENYL)-6-FLUORO-1,4-DIHYDRO-4-OXO-, (+/-)-
NCGC00167536-01
7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Tosufloxacin 100 microg/mL in Acetonitrile
tosufloxacinum
rac-tosufloxacin
SR-01000763339
(RS)-tosufloxacin
racemic tosufloxacin
( inverted exclamation markA)-7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic aci
(+-)-tosufloxacin
SCHEMBL34354
CHEMBL273348
DTXCID0024135
CHEBI:77573
GTPL12878
Tosufloxacin;100490-36-6
J01MA22
HMS2090B18
BCP12643
HY-B1802
RKL10085
BDBM50230834
AKOS015960741
AC-3509
NCGC00167536-02
1,8-Naphthyridine-3-carboxylicacid,7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
7-(3-aminopyrrolin-1-yl)-1-(2,4-diflurophenyl)-1.4-dihydro-6-fluoro-4-oxo-1,8-napthyridine-3-carboxylic acid
TS-09981
CS-0013843
NS00011866
D02317
AB00698260-12
AB00698260-14
EN300-19766363
Q3995932
SR-01000763339-3
BRD-A41450521-003-02-7
BRD-A41450521-075-10-8
Z2681892005
()-7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic aci
7-(3-Amino-1-pyrrolidinyl-1-(2,4-diflurophenyl)-6-fluro-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylicacid
rac-7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Solubility of 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
The solubility of 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid (C18H20F3N5O4) is influenced by several factors such as its molecular structure, polarity, and the presence of functional groups. Understanding its solubility is crucial for various applications in pharmaceutical and chemical disciplines.
Key Factors Affecting Solubility:
As a general observation, compounds that are either highly polar or contain ionic characteristics tend to be soluble in water, while those with significant nonpolar characteristics exhibit low solubility. In this case, the balance between the polar carboxylic acid and the bulky fluorinated aromatic ring is crucial.
To summarize: “Like dissolves like” is a guiding principle when assessing solubility. This compound may demonstrate moderate solubility in water, with potential for improved solubility in organic solvents.