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Ginkgolide C

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Identification
Molecular formula
C20H24O9
CAS number
15291-76-6
IUPAC name
7-(3-furyl)-19-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,15-dione
State
State

At room temperature, Ginkgolide C is in a solid state, existing as a crystalline solid.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
388.00
Boiling point (Kelvin)
661.00
General information
Molecular weight
424.44g/mol
Molar mass
424.4350g/mol
Density
1.5900g/cm3
Appearence

Ginkgolide C appears as a colorless crystalline solid.

Comment on solubility

Solubility of 7-(3-furyl)-19-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,15-dione (C20H24O9)

The solubility of 7-(3-furyl)-19-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,15-dione in various solvents can be intriguing due to its complex structure and functional groups. Generally, the solubility can be influenced by factors such as the presence of polar or nonpolar functional groups and the overall molecular framework. Notably, here are some aspects to consider:

  • Polar solvents: Compounds containing hydroxyl (-OH) groups typically demonstrate improved solubility in polar solvents, such as water or alcohols. The presence of the hydroxyl group in this compound may enhance its compatibility with those polar media.
  • Nonpolar solvents: The extensive hydrocarbon framework suggests that the compound may also show solubility in nonpolar solvents like hexane or toluene. This could make it versatile in certain application areas.
  • Temperature dependence: Solubility can also vary with temperature, often increasing with higher temperatures for many organic compounds. Hence, the evaluation of solubility at different temperatures could reveal a more comprehensive profile.
  • Concentration factors: At varying concentrations, the solubility behavior can differ significantly, showcasing a complex interplay that often requires experimental determination to understand fully.

In summary, while the specific solubility of C20H24O9 may require empirical testing, its structural characteristics suggest potential solubility in a range of solvents, each influenced by its unique molecular interactions. As is often the case, "to understand solubility is to understand the compound itself!"

Interesting facts

Exploring 7-(3-furyl)-19-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,15-dione

This intriguing compound is a member of a unique family of organic molecules characterized by an intricate structure and a variety of functional groups. Here are some fascinating points about this compound:

  • Complex Structure: The compound features a pentacyclic framework, which is notable for its highly fused ring system. This complexity often translates to interesting physical and chemical properties.
  • Furan Ring Influence: The presence of a 3-furyl moiety introduces significant aromatic character, which may influence its reactivity and interactions. Furans are known for their diverse applications in organic synthesis and medicinal chemistry.
  • Hydroxy Group Versatility: The hydroxy group at the 19-position can participate in a variety of chemical reactions, making it a potential site for further derivatization or functionalization. Hydroxy groups are important in enhancing the polarity and solubility of organic compounds.
  • Potential Biological Activity: Compounds of this nature often exhibit interesting biological properties, and variations of pentacyclic compounds have been investigated for *anticancer, antifungal,* and *antibacterial* activity. This makes such compounds worthy of study in medicinal chemistry.
  • Stereochemistry Considerations: The structural complexity also implies several possible stereoisomers, which can lead to variations in biological activity. The stereoelectronic effects introduced by different substituents can have profound impacts on a compound's properties.

In summary, 7-(3-furyl)-19-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,15-dione is not just a chemical entity but a fascinating subject that bridges the fields of organic chemistry, pharmacology, and materials science. As research continues, uncovering its potential applications in various fields could lead to significant advancements.

Synonyms
7-Deacetoxy-7-hydroxygedunin
GEDUNIN DEACETYL-
NSC309912
CHEMBL1981983
DTXSID80908212
HCEYJYMNIQHPPK-UHFFFAOYSA-N
NSC-309912
16,17-Seco-24-nor-5.alpha.,13.alpha.,14.beta.,17.alpha.-chola-1,20,22-trien-16-oic acid, 14,15.beta.:21,23-diepoxy-7.alpha.,17-dihydroxy-4,4,8-trimethyl-3-oxo-, 16,17-lactone
D-Homo-24-nor-17-oxachola-1,20,22-triene-3,16-dione, 14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-, (5.alpha.,7.alpha.,13.alpha.,14.beta.,15.beta.,17a.alpha.)-
NCI60_002663
1-(3-Furyl)-5-hydroxy-4b,7,7,10a,12a-pentamethyl-1,5,6,6a,7,10a,10b,11,12,12a-decahydronaphtho[2,1-f]oxireno[2,3-d]isochromene-3,8(3ah,4bh)-dione #
10-(Furan-3-yl)-6-hydroxy-4,4,6a,10a,12b-pentamethyl-4a,5,6,6a,10,10a,11,12,12a,12b-decahydrooxireno[c]phenanthro[1,2-d]pyran-3,8(4H,7aH)-dione
16,13.alpha.,14.beta.,17.alpha.-chola-1,20,22-trien-16-oic acid, 14,15.beta.:21,23-diepoxy-7.alpha.,17-dihydroxy-4,4,8-trimethyl-3-oxo-, 16,17-lactone
D-Homo-24-nor-17-oxachola-1,22-triene-3,16-dione, 14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-, (5.alpha.,7.alpha.,13.alpha.,14.beta.,15.beta.,17a.alpha.)-