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Rosuvastatin

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Identification
Molecular formula
C22H28FN3O6S
CAS number
147098-20-2
IUPAC name
7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid
State
State

At room temperature, Rosuvastatin is a solid. It is typically available in the form of tablets or capsules for medical use.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.20
Boiling point (Celsius)
345.20
Boiling point (Kelvin)
618.40
General information
Molecular weight
481.54g/mol
Molar mass
481.5390g/mol
Density
1.3593g/cm3
Appearence

Rosuvastatin is a white or near-white powder, which is hygroscopic, meaning it can absorb moisture from the air. The powder can be pressed into solid forms for pharmaceutical applications.

Comment on solubility

Solubility of 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid

The solubility of 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid (C22H28FN3O6S) is influenced by several key factors:

  • Polarity: The presence of multiple hydroxyl groups in the structure typically enhances solubility in polar solvents, particularly water.
  • Hydrophobic Regions: The trifluoromethyl and phenoxy groups contribute to hydrophobic characteristics, which may limit solubility in purely aqueous environments.
  • pH Dependency: Being an acid, the solubility can be highly pH-dependent, generally increasing in alkaline conditions where the carboxylic acid group ionizes.
  • Temperature Effects: Like many organic compounds, solubility can also be enhanced with increased temperature, potentially allowing for better solvent interactions.

Overall, one can expect a moderate to good solubility in alcohols and possibly some organic solvents, while aqueous solubility may vary based on the environmental pH and temperature conditions. It is important to consider these aspects when dealing with this compound in practical applications.

Interesting facts

Interesting Facts About 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid

This compound, often referred to in the scientific community as a specialized derivative with considerable biochemical significance, showcases a remarkable structure that contributes to its unique properties. Here are some fascinating points deserving of attention:

  • Complex Structure: The presence of multiple functional groups, including hydroxyl groups and a trifluoromethyl moiety, allows this compound to engage in a variety of chemical reactions, enhancing its biological activity.
  • Biological Relevance: Compounds like this one are often studied for their role in pharmaceuticals. They may interact with biological targets, potentially leading to the development of new therapeutic agents.
  • Fluorine's Impact: The trifluoromethyl group in its structure is known for its ability to enhance lipophilicity and metabolic stability, often leading to increased efficacy in medicinal applications.
  • Natural Product Inspiration: The intricate design of this compound is reminiscent of natural products, which often serve as the basis for synthetic derivatives aimed at improving medicinal properties.
  • Research Opportunities: Ongoing research in academia and industry continues to explore the various applications of this compound — from understanding its mechanism of action to discovering novel derivatives with enhanced properties.

It is essential to recognize that the exploration of such compounds involves a multidisciplinary approach, encompassing areas like organic synthesis, pharmacology, and biochemistry. As announced by prominent chemists, "Understanding the intricacies of compound functionalities opens the pathway to innovative solutions in health and science."

In summary, 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid is not just a chemical formula; it is a gateway to new discoveries in drug design and development, making it an exciting topic for both scientists and chemistry students alike.

Synonyms
15(S)-Fluprostenol
7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid
54276-24-3
DTXSID10860576
WWSWYXNVCBLWNZ-UHFFFAOYSA-N
73307-38-7
HLA55019
7-(3,5-dihydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl)hept-5-enoic acid
NS00018045