Cefotaxime | Solubility of Things

Identification

Molecular formula

C₁₆H₁₇N₅O₇S₂

CAS number

64485-93-4

IUPAC name

7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

State

At room temperature, Cefotaxime is a solid.

Melting point (Celsius)

161.00

Melting point (Kelvin)

434.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

455.45g/mol

Molar mass

455.4480g/mol

Density

1.5000g/cm³

Appearence

Cefotaxime appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility Analysis

The solubility of the compound 7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C₁₆H₁₇N₅O₇S₂) can be influenced by several factors, including its chemical structure and functional groups present.

Factors Affecting Solubility

Several key factors impact the solubility of this compound:

Polarity: Due to the presence of multiple functional groups such as carboxylic acids and amino groups, the compound is likely to possess polar characteristics, enhancing its solubility in polar solvents like water.
Hydrophobic Interactions: The presence of thia and dithietane rings may introduce hydrophobic regions, which could reduce solvency in highly polar solvents.
Temperature: As with many organic compounds, increasing temperature may improve solubility due to enhanced molecular motion.
pH Level: The solubility of the carboxylic acid moieties can vary widely with pH, where deprotonation can lead to improved solubility in aqueous media.

Overall, while the compound may display moderate to high solubility in polar solvents, particularly aqueous solutions, its precise solubility requires empirical testing to determine its behavior under varied conditions.

Interesting facts

Interesting Facts about 7-[[4-(2-amino-1-carboxy-2-oxo-ethylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This fascinating compound is a complex organic molecule that showcases the intricate relationships between functional groups, structure, and biological activity. Here are some engaging points to consider:

Structural Complexity: The compound features a bicyclic structure that is characteristic of many biologically active compounds, resembling a bridge between two cycles.
Functional Diversity: The presence of multiple functional groups, including carboxylic acids and amines, suggests that this compound could exhibit a variety of chemical reactivity and biological interactions.
Potential Therapeutic Roles: Given its structural features, it is possible that this compound could play a role in pharmaceuticals, possibly as an antimicrobial or anticancer agent, highlighting the importance of structure-activity relationships in drug design.
Sulfur Chemistry: The inclusion of sulfur in the structure, particularly in several thia groups, might contribute to unique properties, including electron donation capabilities and redox behavior.
Research Implications: The compound serves as a potential lead for further research in medicinal chemistry, where it can be studied for its efficacy and mechanism of action against specific diseases.

As an aspiring chemist, it’s essential to appreciate both the structural beauty and the potential applications of complex compounds like this. Understanding these complex molecules allows scientists to innovate and discover new therapeutic agents that could change lives.