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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[7-acetonyl-6-[[4-(dimethylamino)-3-hydroxy-5-(4-hydroxy-2,4,6-trimethyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-6-methyl-tetrahydropyran-2-yl]methoxy]-10-hydroxy-5,9,16-trimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
State
State

At room temperature, erythromycin is typically in a solid state.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2400g/cm3
Appearence

Erythromycin appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of the Compound

The compound 7-acetonyl-6-[[4-(dimethylamino)-3-hydroxy-5-(4-hydroxy-2,4,6-trimethyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-6-methyl-tetrahydropyran-2-yl]methoxy]-10-hydroxy-5,9,16-trimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate (C37H67NO13) exhibits unique solubility characteristics primarily influenced by its complex structure.

Key Factors Affecting Solubility:

  • Hydrophobic vs. Hydrophilic Regions: This compound possesses both hydrophobic alkyl chains and hydrophilic groups, which can affect its solubility in various solvents.
  • Polar Functional Groups: The presence of functional groups such as hydroxyl (–OH) can enhance solubility in polar solvents like water, while non-polar regions might favor solubility in organic solvents.
  • Molecular Size and Weight: With a large molecular weight (C37H67NO13), solubility may be limited in some solvents that typically dissolve smaller molecules.

Typically, compounds of this nature are more soluble in organic solvents such as:

  • Ethyl acetate
  • Dichloromethane
  • Acetone

While it may show some degree of solubility in water due to the polar functional groups, the solubility is generally considered limited. Therefore, assessing the solubility in specific solvents is essential for practical applications.

In summary, the solubility profile of this compound signifies a balance between its hydrophobic and hydrophilic characteristics, making it an intriguing subject of study in the realm of chemical compounds.

Interesting facts

Interesting Facts about 7-acetonyl-6-[[4-(dimethylamino)-3-hydroxy-5-(4-hydroxy-2,4,6-trimethyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-6-methyl-tetrahydropyran-2-yl]methoxy]-10-hydroxy-5,9,16-trimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate

This remarkable compound is part of a class of molecules known for their significant biological activities, which makes it a subject of interest in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Complex Structure: The compound boasts a highly intricate structure, featuring multiple functional groups that contribute to its reactivity and properties. The presence of both hydroxy and methoxy groups enhances its potential for various interactions.
  • Biological Activity: Compounds like this one are frequently studied for their pharmacological effects, as they may exhibit properties such as anti-inflammatory, antimicrobial, or anticancer activities. The unique arrangement of substituents often dictates their mechanism of action.
  • Synthetic Pathways: The synthesis of such complex organic compounds typically involves multiple steps and specialized reactions. Understanding these pathways not only provides insights into their functionality but also helps chemists develop more efficient synthetic methods.
  • Research Applications: Due to its distinct structure, this compound may have applications in drug development processes. Researchers are continuously investigating its potential to lead to novel therapeutic agents.
  • Chemical Insights: The presence of a tetrahydropyran motif suggests interesting ring-opening and ring-closing reactions that could be utilized for further chemical transformations or in designing other bioactive compounds.

As a compound with a vast array of functional groups, studying 7-acetonyl-6-[[4-(dimethylamino)-3-hydroxy-5-(4-hydroxy-2,4,6-trimethyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-6-methyl-tetrahydropyran-2-yl]methoxy]-10-hydroxy-5,9,16-trimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate not only enhances our understanding of organic chemistry but also ignites curiosity about the vast possibilities within the pharmaceutical realm.