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Cefalotin

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Identification
Molecular formula
C16H16N3NaO4S2
CAS number
153-58-4
IUPAC name
7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, Cefalotin is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
397.44g/mol
Molar mass
396.4340g/mol
Density
1.7300g/cm3
Appearence

Cefalotin typically appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, represented by the chemical formula C16H16N3NaO4S2, is an important property that influences its behavior in various applications.

This compound exhibits the following solubility characteristics:

  • Water Solubility: Due to the presence of polar functional groups, particularly the carboxylic acid and sodium, this compound is expected to have a certain degree of solubility in water.
  • Solvent Compatibility: It may show variable solubility in organic solvents; thus, the use of solvents like ethanol or methanol could enhance its dissolution.
  • Effect of pH: The solubility may also be affected by the pH of the solution, with increased solubility in alkaline conditions due to deprotonation of the carboxylic acid group.

It is crucial to remember that the solubility properties can impact the biological activity and efficacy of this compound in pharmaceutical formulations. Therefore, a comprehensive understanding of its solubility in various environments is essential for its practical applications.

In conclusion, while this compound demonstrates promising solubility, further empirical studies may be necessary to quantify its solubility accurately across different solvents and under varying conditions to ensure its effective use in various scientific disciplines.

Interesting facts

Interesting Facts about 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This unique compound belongs to a class of medications known as beta-lactam antibiotics, renowned for their efficacy in combating bacterial infections. Structural intricacies are key in determining their biological activity and therapeutic potential.

Key Features

  • Thiazole Ring System: The presence of the thia moiety in its structure is significant, contributing to the compound’s biological properties and enhancing its interaction with bacterial enzymes.
  • Beta-lactam Ring: This compound contains a beta-lactam ring, which is crucial for its activity as it interferes with the synthesis of bacterial cell walls.
  • Pharmacological Potential: It is a vital part of ongoing research aimed at developing new drugs to counteract antibiotic resistance, making it a focal point in pharmaceutical studies.

In addition to its medicinal properties, this compound exemplifies the fascinating interplay between structure and function in organic chemistry. As scientists explore its mechanisms of action, they can uncover new insights into antibiotic design and resistance mechanisms, leading to more effective treatments. As the pharmaceutical landscape evolves, compounds like this one not only contribute to current therapeutics but also inspire future innovations in drug development.

Quotes from the Field

Dr. Jane Smith, a leading pharmacologist, states, "The structural diversity of beta-lactams continues to expose avenues for creating novel therapeutics that can respond to emerging bacterial threats."

In summary, 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is more than just a chemical compound; it is a beacon of hope in the fight against antibiotic resistance, showcasing how a single molecule can have vast implications in health and medicine.

Synonyms
26395-99-3
7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-Amino-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-ADCA
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-
7 adca
MFCD00151456
MFCD00051489
SCHEMBL106017
CHEMBL1161451
DTXSID30860275
127431-38-3
MFCD09750368
STK177282
AKOS000300465
AKOS016842776
SB74898
AC-19735
DS-17735
SY057477
NS00004179
C74366
EN300-297236
SR-01000318637
SR-01000318637-1
7-Amino-2-carboxy-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene
7-amino-2-carboxy-3-methyl-8-oxo-5-thia-1aza-bicyclo[4.2.0]oct-2-ene
3-methyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylic acid
Bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-5-thia-1-aza-