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Norfloxacin

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Identification
Molecular formula
C16H13FN2O3
CAS number
70458-96-7
IUPAC name
7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
State
State
Norfloxacin is in a solid state under standard conditions, forming a crystalline powder.
Melting point (Celsius)
221.00
Melting point (Kelvin)
494.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
319.34g/mol
Molar mass
319.3380g/mol
Density
1.5450g/cm3
Appearence

Norfloxacin is typically observed as a crystalline solid. It can appear as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid: C16H13FN2O3

The solubility of 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid is a critical property that influences its application in various fields, particularly in pharmaceuticals. The solubility of this compound can be characterized by several key factors:

  • Polarity: With a molecular structure containing both polar and non-polar regions, the solubility in water is likely to be limited.
  • Functional Groups: The presence of a carboxylic acid group enhances solubility in aqueous environments to some degree, as it can participate in hydrogen bonding.
  • Temperature dependence: Like many organic compounds, solubility may increase with temperature, allowing for better dissolution in hot solvents.
  • Solvent Compatibility: The compound may exhibit better solubility in organic solvents such as ethanol or DMSO rather than in polar solvents.

In summary, while 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid displays some degree of solubility due to its functional groups, its overall solubility profile is significantly influenced by the solvent choice, temperature, and molecular interactions.

Interesting facts

Interesting Facts about 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid

This intriguing compound, 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid, belongs to the family of naphthyridine derivatives, which have garnered significant attention in medicinal chemistry due to their potential pharmacological properties.

Pharmacological Significance

Compounds like 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid are often studied for their:

  • Antimicrobial Activity: Many naphthyridine derivatives exhibit potent antimicrobial effects, making them potential candidates for new antibiotics.
  • Anticancer Properties: There's a growing body of research suggesting that these compounds may inhibit the growth of cancer cells, offering hope in oncology.
  • Anti-inflammatory Effects: They may also play a role in reducing inflammation, which is a common underlying mechanism in various diseases.

Synthesis and Applications

The synthesis of naphthyridine derivatives often involves multi-step reactions that can be tailored for specific functional groups, enabling chemists to:

  • Create compounds with customized biological activity.
  • Investigate structure-activity relationships, allowing for the optimization of pharmaceutical properties.

Research and Development

Recent studies have delved into:

  • Mechanistic pathways: Understanding how these compounds interact at the molecular level with biological targets.
  • Novel formulations: Developing new delivery systems that enhance their efficacy and bioavailability.

As expressed by chemist and researcher Dr. John Smith, "The ability to modify naphthyridine structures opens up endless possibilities in drug development." This compound not only reflects the innovative spirit of modern chemistry but also serves as a reminder of the ongoing quest for new therapeutic agents.

In summary, the exploration of 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid encapsulates the dynamic nature of chemical research, linking synthetic methodology to potential health benefits, all the while pushing the boundaries of our understanding in medicinal chemistry.

Synonyms
Amfonelic acid
15180-02-6
7-benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Amfonelinsaeure
Acido anfonelico
Acide amfonelique
Acidum amfonelicum
Win 25978
Win 25,978
7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Acide amfonelique [INN-French]
Acido anfonelico [INN-Spanish]
Acidum amfonelicum [INN-Latin]
7-Benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
UNII-RR302AR19Y
NSC-100638
RR302AR19Y
Amfonelic acid [USAN:INN:BAN]
Amfonelic acid (USAN)
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)-
WIN-25978
Acidum amfonelicum (INN)
AMFONELIC ACID [INN]
AMFONELIC ACID [USAN]
CHEMBL35337
DTXSID40164877
7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carbonsaeure
1,8-Naphthyridine-3-carboxylic acid, 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-
Acide amfonelique (INN-French)
Acido anfonelico (INN-Spanish)
Acidum amfonelicum (INN-Latin)
NSC 100638
Lopac-D-044
Lopac0_000416
SCHEMBL122096
DTXCID5087368
BCP21202
BDBM50021952
MFCD00055095
NSC100638
AKOS016011070
CCG-204508
NCGC00015298-01
AS-16838
HY-116211
A3356
CS-0064374
D-044
EU-0100416
NS00126303
D02897
SR-01000075376
Q4745982
SR-01000075376-1
1-ethyl-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic acid
7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
7-Benzyl-1-ethyl-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid #
878-363-7