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Bromazepam

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Identification
Molecular formula
C14H10BrN3O
CAS number
1812-30-2
IUPAC name
7-bromo-1-[3-(dimethylamino)propyl]-5-(2-pyridyl)-3H-1,4-benzodiazepin-4-ium-2-one
State
State

At room temperature, bromazepam is in a solid state. It is usually available in tablet form when formulated as a medication, but as a pure compound, it is a powder.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
316.15g/mol
Molar mass
316.2090g/mol
Density
1.2440g/cm3
Appearence

Bromazepam is typically a white to yellowish crystalline powder. It is odorless and has a bitter taste. Its crystalline form gives it a visually distinct appearance which can be identified in quality control processes.

Comment on solubility

Solubility Overview

The solubility of the compound 7-bromo-1-[3-(dimethylamino)propyl]-5-(2-pyridyl)-3H-1,4-benzodiazepin-4-ium-2-one can be characterized through various parameters that influence its behavior in different solvents. Here are some key points to consider:

Factors Affecting Solubility

  • Polarity: Since this compound contains both polar and nonpolar functional groups, its overall solubility will vary depending on the solvent used, making it more soluble in polar solvents.
  • pH: Being a quaternary ammonium compound, its solubility can significantly change with the pH of the solution, with higher solubility often observed in more basic environments.
  • Hydrophobic Interactions: The presence of the pyridine ring and the bromine substituent may enhance hydrophobic interactions, potentially leading to decreased solubility in highly polar solvents.

General Solubility Considerations

In general, solubility is often assessed by:

  • Conducting solubility tests in various solvents such as water, ethanol, and organic solvents.
  • Utilizing the like dissolves like principle, which suggests that the compound will be more soluble in solvents with similar polarities.
  • Investigating temperature effects, as solubility can increase with elevated temperatures for many organic compounds.

In summary, while the solubility of 7-bromo-1-[3-(dimethylamino)propyl]-5-(2-pyridyl)-3H-1,4-benzodiazepin-4-ium-2-one may present some challenges due to competing factors, careful analysis can lead to improved understanding of its behavior in different solvent systems.

Interesting facts

Interesting Facts about 7-Bromo-1-[3-(dimethylamino)propyl]-5-(2-pyridyl)-3H-1,4-benzodiazepin-4-ium-2-one

This compound, a member of the benzodiazepine class, is known for its intricate structure and potential pharmacological applications. With a unique arrangement of atoms, it exhibits notable properties that make it a subject of interest in the field of medicinal chemistry. Here are some fascinating aspects:

  • Structural Diversity: The presence of both a bromine atom and a dimethylamino group contributes to the compound's reactivity and interactions with biological systems.
  • Pyridine Integration: The incorporation of a 2-pyridyl group enhances its ability to bind to various receptors, potentially influencing its pharmacological effects.
  • Potential Applications: Research indicates that certain benzodiazepines may exhibit anxiolytic and sedative properties, which could be useful in treating disorders related to anxiety and sleep.
  • Research Significance: Continuous studies are being conducted to explore the therapeutic potential of similar compounds, emphasizing the importance of structural modifications in drug design.

As scientists delve deeper into understanding the mechanisms of action, compounds like this one demonstrate the exciting intersection of chemistry and medicine, ultimately paving the way for novel therapies. In the words of a fellow researcher, "Every compound tells a story—the challenge is to uncover its chapters." This benzodiazepine, with its rich structure and potential, is surely one of them.