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7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole

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Identification
Molecular formula
C8HBrCl3F3N2
CAS number
84654-84-2
IUPAC name
7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole
State
State

This compound is a solid at room temperature, exhibiting stability and maintaining its structure in typical ambient conditions.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
374.35g/mol
Molar mass
374.3490g/mol
Density
2.1600g/cm3
Appearence

The compound is typically a solid. It may appear as a crystalline powder or a solid lump, depending on how it has been processed.

Comment on solubility

Solubility of 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole

The solubility of 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole is a complex matter due to its unique structural characteristics. This compound is a member of the benzimidazole family, known for their diverse chemical properties. When evaluating its solubility, several factors come into play:

  • Polarity: The presence of multiple halogen substituents (bromine and chlorine) along with the trifluoromethyl group often leads to significant polarity, affecting water solubility.
  • Hydrophobic Interactions: The bulky halogen atoms may create hydrophobic properties that encourage solubility in organic solvents rather than in polar solvents like water.
  • Temperature Influence: As with many organic compounds, solubility might increase with temperature, although this can vary depending on the specific solvent system used.
  • Solvent Compatibility: This compound is likely to dissolve better in non-polar or weakly polar solvents such as chloroform, dichloromethane, or similar organic compounds.

In summary, while the precise solubility of 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole may not be readily documented, one can anticipate that it would exhibit limited solubility in water, coupled with a greater affinity for organic solvents. It reflects the broader trend of many halogenated organic compounds, which often display preference towards non-aqueous environments.

Interesting facts

Interesting Facts About 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole

The compound 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating example of a halogenated benzimidazole derivative, which showcases the diversity of chemical modifications that can significantly alter a compound's properties and applications.

Key Highlights:

  • Biological Activity: Benzimidazole derivatives are known for their wide range of biological activities. Some of these compounds exhibit antibacterial, antiviral, and even antifungal properties, making them considerable candidates in pharmaceutical research.
  • Environmental Impact: The halogen substitutions in this compound may also affect its environmental persistence and toxicity, which are crucial factors constantly studied in environmental chemistry.
  • Synthetic Versatility: The synthetic routes leading to this compound can be complex but allow for functionalization that can yield varied compounds used in agrochemicals and pharmaceuticals.
  • Analytical Techniques: This compound can be analyzed using various methods, including NMR and mass spectrometry, which help chemists identify its structure and confirm its purity.

For researchers involved in the study of heterocyclic compounds, this particular molecule offers not only a challenge in synthesis but also an opportunity to explore its potential applications in various fields such as medicinal chemistry and material science.

As chemists continue to investigate the properties and applications of compounds like 7-bromo-4,5,6-trichloro-2-(trifluoromethyl)-1H-benzimidazole, they often reflect on the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." This encourages innovation and exploration within the chemical sciences.

Synonyms
BRN 0961953
BENZIMIDAZOLE, 4-BROMO-5,6,7-TRICHLORO-2-(TRIFLUOROMETHYL)-
4-Bromo-5,6,7-trichloro-2-(trifluoromethyl)benzimidazole
4228-93-7
DTXSID20195109
DTXCID80117600
KMFHVMJKOGJJRE-UHFFFAOYSA-N