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Clonazepam

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Identification
Molecular formula
C15H10ClN2O3
CAS number
1622-61-3
IUPAC name
7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium;chloride
State
State

Clonazepam is in the solid state at room temperature. It is generally stable under regular conditions but must be stored in a tightly closed container to prevent degradation.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
227.00
Boiling point (Kelvin)
500.15
General information
Molecular weight
353.22g/mol
Molar mass
313.7210g/mol
Density
1.4200g/cm3
Appearence

Clonazepam typically appears as a white to off-white crystalline powder. It is odorless and has no identifiable taste. The compound is often provided as a prescription medication in tablet or liquid form when used pharmaceutically.

Comment on solubility

Solubility Insights for 7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium Chloride

The solubility of 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium chloride is influenced by several chemical properties. Understanding the solubility is crucial for applications in pharmacology and other fields. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of the chloride ion contributes to the overall polarity of the compound, enhancing its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: This compound may engage in hydrogen bonding due to the presence of acidic hydrogen on the nitrogen atoms, which can increase solubility in water.
  • Solvent Compatibility: It demonstrates variable solubility in organic solvents, usually showing better solubility in alcohols and less in non-polar solvents.
  • pH Dependence: The solubility can change with pH levels, as ionization may alter the structure, affecting solubility dynamics.
  • Temperature Influence: Higher temperatures often increase the solubility of most salts, and this compound is likely no exception.

In summary, the solubility characteristics of 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium chloride can be described as:

  1. Highly soluble in polar solvents.
  2. Moderate solubility in various organic solvents.
  3. The pH level and temperature can significantly influence its solubility.

The intricate balance between its chemical structure and environmental factors makes studying its solubility both fascinating and complex.

Interesting facts

Interesting Facts about 7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium; Chloride

This compound is a member of the benzodiazepine family, which is renowned for its psychoactive properties. Benzodiazepines are primarily known for their effects on the central nervous system, often being used as anxiolytics and sedatives. Here are some interesting aspects of this particular compound:

  • Medical Applications: Due to its structure, this compound may exhibit potential therapeutic benefits, including anxiolytic, sedative, or muscle relaxant effects.
  • Synthetic Pathways: The synthesis of this compound often involves various chemical reactions, including the formation of the benzodiazepine ring, providing students and chemists with a fascinating insight into organic synthesis techniques.
  • Chlorine's Role: The presence of the chloro group enhances the biological activity of the compound and can influence its binding affinity to neuronal receptors, making it a critical feature in the design of new drugs.
  • Research Interest: Continuous studies focus on this compound's various derivatives, contributing to the interdisciplinary fields of pharmacology, medicinal chemistry, and neuropharmacology.

The exploration of compounds like this one emphasizes the significance of structure-activity relationships (SAR) in drug design and discovery. As researchers delve deeper into the mechanisms and effects of benzodiazepines, compounds such as 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-ium become crucial in understanding neurological disorders and developing effective treatments.

As with any benzodiazepine derivative, it is also essential to consider aspects such as side effects and dependency potential when assessing its use in medical applications. The journey of understanding this compound not only enriches the field of chemistry but also holds practical implications for the advancement of health sciences.

Synonyms
Elbrus