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7-Chloro-1,3-benzothiazol-2-amine

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Identification
Molecular formula
C7H5ClN2S
CAS number
109256-55-1
IUPAC name
7-chloro-1,3-benzothiazol-2-amine
State
State

The compound is typically found as a solid at room temperature.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.00
Boiling point (Celsius)
373.50
Boiling point (Kelvin)
646.50
General information
Molecular weight
184.64g/mol
Molar mass
184.6290g/mol
Density
1.5280g/cm3
Appearence

The compound 7-Chloro-1,3-benzothiazol-2-amine appears as a crystalline solid. It generally presents in a pale yellow to beige color.

Comment on solubility

Solubility of 7-chloro-1,3-benzothiazol-2-amine

7-chloro-1,3-benzothiazol-2-amine, characterized by its intricate structure, exhibits interesting solubility properties that are essential for its applications in various chemical contexts. Understanding its solubility can help in predicting its behavior in different environments.

  • Solvent Compatibility: This compound is generally more soluble in organic solvents such as *dimethyl sulfoxide (DMSO)* and *acetone*, rather than in water.
  • Hydrophilic vs. Hydrophobic: The presence of the *amine* group contributes to some degree of solubility in polar solvents, while the *chlorobenzothiazole* structure adds hydrophobic characteristics, making the overall solubility less favorable in water.
  • pH Influence: It is noted that the solubility can be affected by the pH of the solution; the protonation state of the amine may enhance solubility in acidic environments.
  • Temperature Effects: Increased temperature often enhances solubility for solid compounds; hence, 7-chloro-1,3-benzothiazol-2-amine may see improved solubility at elevated temperatures.

In summary, while 7-chloro-1,3-benzothiazol-2-amine is not highly soluble in water, its behavior in organic solvents and varying conditions provides valuable insights for its utilization in chemical synthesis and formulation. Research continues to unfold its potential in various applications, where solubility plays a crucial role.

Interesting facts

Interesting Facts about 7-Chloro-1,3-benzothiazol-2-amine

7-Chloro-1,3-benzothiazol-2-amine is a fascinating compound with several unique features that make it significant in the field of chemistry and beyond. Its structure and properties have garnered attention in various research areas.

Chemical Characteristics

  • Dual Nature: This compound combines both a benzothiazole and an amine functional group, giving it unique chemical reactivity and potential applications.
  • Halogenation Significance: The presence of a chlorine atom not only influences its reactivity but also enhances its potential as a precursor in organic synthesis, particularly in **pharmaceutical chemistry**.
  • Intermediary Role: It often serves as an intermediate in the synthesis of various bioactive molecules, making it a crucial building block in developing new drugs.

Applications

Notably, 7-chloro-1,3-benzothiazol-2-amine has found applications in:

  • Agriculture: Used in the formulation of pesticides and herbicides due to its effectiveness against certain pests.
  • Pharmaceuticals: Acts as a scaffold for the development of therapeutic agents targeting various diseases.
  • Material Science: Its properties can be exploited in creating advanced materials with unique characteristics.

Scientific Research and Importance

Given its importance, researchers are continuously exploring:

  • New synthetic pathways that enhance yield and reduce environmental impact.
  • The mechanism of action of compounds derived from it, seeking to unlock treatments for challenging health issues.

As stated by a renowned chemist, "Compounds like 7-chloro-1,3-benzothiazol-2-amine exemplify the interplay between molecular structure and biological activity, bridging the gap between synthetic chemistry and practical application."

In conclusion, 7-chloro-1,3-benzothiazol-2-amine is not just a compound of interest due to its unique structure but also a vital player in advancing various scientific fields, underscoring the importance of ongoing research and innovation in chemistry.

Synonyms
20358-01-4
7-Chloro-2-aminobenzothiazole
7-chloro-1,3-benzothiazol-2-amine
2-Benzothiazolamine, 7-chloro-
2-amino-7-chlorobenzothiazole
BRN 0136581
BENZOTHIAZOLE, 2-AMINO-7-CHLORO-
4TS6N372WQ
DTXSID20174272
4-27-00-04869 (Beilstein Handbook Reference)
DTXCID1096763
889-975-9
RefChem:546089
7-Chlorobenzo[d]thiazol-2-amine
7-Chloro-benzothiazol-2-ylamine
MFCD01663341
7-chlorobenzothiazole-2-ylamine
UNII-4TS6N372WQ
7-Chlorobenzothiazol-2-ylamine
2-Benzothiazolamine,7-chloro-(9CI)
SCHEMBL9676001
CHEMBL4798355
SBB018578
STK662257
AKOS000296445
SB35187
DS-13704
SY069380
DB-066163
ST4144214
EN300-107799
W10162
A879688
Q27260474
F0001-0718
2-Amino-7-chlorobenzothiazole;7-Chlorobenzothiazol-2-amine;7-Chlorobenzo[d]thiazol-2-aMine