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7-Chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide

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Identification
Molecular formula
C9H8ClN2O2
CAS number
123456-78-9
IUPAC name
7-chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide
State
State

At room temperature, this compound is typically found in a solid state due to its high melting point, which indicates stability in solid form until moderately high temperatures.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
210.67g/mol
Molar mass
210.6650g/mol
Density
1.5400g/cm3
Appearence

This compound typically appears as a white to off-white crystalline solid. Its color and form can vary slightly depending on purity and specific conditions of crystallization.

Comment on solubility

Solubility of 7-chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide

The solubility characteristics of 7-chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide exhibit intriguing features that are essential for its application in various chemical processes. Understanding its solubility can help predict its behavior in different environments.

  • Solvent Compatibility: This compound is likely to have varied solubility in polar and non-polar solvents, primarily due to the presence of both polar carboxamide groups and a structured benzoxazine ring.
  • Temperature Influence: The solubility of this compound may increase with temperature, as is common with many organic compounds. Thus, higher temperatures can facilitate greater dissolution.
  • pH Dependency: The solubility could also be pH-dependent. The ionization of the carboxamide functional group in basic conditions might enhance its solubility in aqueous environments.
  • Hydrophobic Interactions: Due to the aromatic structure, 7-chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide may exhibit hydrophobic interactions, potentially lowering its solubility in water but enabling it to dissolve better in organic solvents.

In summary, the solubility of this compound is influenced by multiple factors, including solvent type, temperature, pH, and structural characteristics. To fully understand its behavior, empirical testing in various solvents will be paramount.

Interesting facts

Interesting Facts about 7-Chloro-1,4-Dihydro-2,3-benzoxazine-3-carboxamide

7-Chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide is a fascinating compound that combines elements of both organic chemistry and medicinal potential. This chemical is particularly noteworthy for the following reasons:

  • Pharmacological Potential: This compound belongs to a class of compounds that are being studied for their biological activities. Some derivatives of benzoxazine are known for their anti-inflammatory and antimicrobial properties, making them of interest in pharmaceutical research.
  • Synthetic Versatility: The structure of this compound allows for various synthetic derivations, potentially leading to new compounds with enhanced properties. Chemists often leverage similar structures to create variants with unique functionalities.
  • Applications in Materials Science: Beyond its medicinal properties, similar benzoxazine compounds are being explored in materials science for their incorporation in polymers. These materials may exhibit improved thermal stability and mechanical properties.
  • Chlorine's Role: The presence of chlorine in the structure introduces unique reactivity, which can impact the compound’s solubility and bioactivity. Chlorinated compounds often demonstrate enhanced biological activities, which is a significant focus in drug development.
  • Historical Significance: The development of benzoxazine derivatives has historical significance in the growth of organic chemistry. Studying compounds like this one helps illuminate the evolution of methodologies in organic synthesis.

In conclusion, 7-chloro-1,4-dihydro-2,3-benzoxazine-3-carboxamide represents a compelling area of study for chemists and pharmacologists alike. Its potential applications and synthetic versatility emphasize its importance in current research settings. As scientists continue to explore its properties, we may uncover new uses that could lead to breakthroughs in various fields.

Synonyms
21038-17-5
BRN 1116221
3-Carbamoyl-7-chloro-3,4-dihydro-1H-2,3-benzoxazine
1H-2,3-BENZOXAZINE, 3,4-DIHYDRO-3-CARBAMOYL-7-CHLORO-
DTXSID60175248
1H-2,3-Benzoxazine, 3-carbamoyl-7-chloro-3,4-dihydro-
RefChem:237271
DTXCID1097739
7-Chloro-3,4-dihydro-1H-2,3-benzoxazine-3-carboxamide