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7-Chloro-2-(3-pyridyl)tetralin-1-one

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Identification
Molecular formula
C15H12ClNO
CAS number
161349-67-9
IUPAC name
7-chloro-2-(3-pyridyl)tetralin-1-one
State
State
At room temperature, this compound is typically a solid, presenting as a crystalline powder.
Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
241.70g/mol
Molar mass
241.7030g/mol
Density
1.3000g/cm3
Appearence

7-Chloro-2-(3-pyridyl)tetralin-1-one is typically found in a solid state at room temperature. This compound appears as an off-white to light yellow crystalline powder. The crystalline nature allows it to have a defined and consistent appearance.

Comment on solubility

Solubility of 7-chloro-2-(3-pyridyl)tetralin-1-one

The solubility of 7-chloro-2-(3-pyridyl)tetralin-1-one can be understood through several key factors:

  • Polarity: The presence of the chloro and pyridyl groups influences the compound's polarity. Typically, more polar compounds tend to dissolve better in polar solvents.
  • Solvent Type: This compound may exhibit variable solubility in different solvents. Common solvents to consider include:
    • Water
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
  • Temperature: As with many chemical compounds, increasing the temperature can enhance solubility. It is essential to assess the compound's behavior at varying temperatures.
  • Concentration: The solubility limit of 7-chloro-2-(3-pyridyl)tetralin-1-one may affect its proper usage in laboratory settings and application in formulations.

In summary, the solubility characteristics of 7-chloro-2-(3-pyridyl)tetralin-1-one are determined by its molecular structure and the interaction with the solvent. Understanding these aspects is crucial for effective utilization.

Interesting facts

Interesting Facts About 7-Chloro-2-(3-pyridyl)tetralin-1-one

7-Chloro-2-(3-pyridyl)tetralin-1-one is a compound that has captured the interest of scientists and researchers due to its unique structure and potential applications. Here are some engaging insights:

Chemical Structure and Functionality

  • Pyridine Ring Contribution: The presence of the 3-pyridyl group imparts distinct electronic properties to the compound, which can influence its reactivity and interactions with biological systems.
  • Chlorine Atom: The 7-chloro substituent enhances the compound's lipophilicity, which is a vital attribute for drug design, especially for targeting specific receptors in the body.

Biological Relevance

  • Potential Therapeutic Uses: Research has indicated that similar compounds may exhibit neuroprotective effects and could be investigated for neurological disorders.
  • Pharmacological Interest: The unique combination of a tetralin scaffold with a pyridine ring opens up avenues for exploring its potential as a lead compound in drug development.

Research and Development

This compound is of particular interest in medicinal chemistry and pharmacology. As students and researchers delve deeper into its properties, they might uncover novel mechanisms of action. The compound exemplifies the intricate relationship between structure and activity, emphasizing how slight modifications can lead to vastly different biological effects.

Fun Fact

Its complex structure serves as a reminder of the beauty of organic chemistry, where even small variations can drastically affect a compound's behavior. As one researcher aptly put it, "In chemistry, the smallest changes often yield the biggest surprises!"

Synonyms
786-97-0
SU 10603
7-Chloro-3,4-dihydro-2-(3-pyridyl)-1(2H)-naphthalenone
BRN 1537666
1(2H)-Naphthalenone, 7-chloro-3,4-dihydro-2-(3-pyridinyl)-
SU-10603
SU-10,603
1(2H)-Naphthalenone, 3,4-dihydro-7-chloro-2-(3-pyridyl)-
5-21-09-00064 (Beilstein Handbook Reference)
1(2H)-NAPHTHALENONE, 7-CHLORO-3,4-DIHYDRO-2-(3-PYRIDYL)-
1(2H)-Naphthalenone, 7-chloro-3,4-dihydro-2-(3-pyridinyl)-(9CI)
7-Chloro-2-(pyridin-3-yl)-3,4-dihydronaphthalen-1(2H)-one
7-chloro-2-pyridin-3-yl-3,4-dihydro-2H-naphthalen-1-one
7-chloro-2-(pyridin-3-yl)-1,2,3,4-tetrahydronaphthalen-1-one
CHEMBL5413242
DTXSID80999882
GLXC-27397
AKOS028110537
DA-60558
HY-116643
CS-0066147