Skip to main content

7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

ADVERTISEMENT
Identification
Molecular formula
C11H9ClN2O3
CAS number
288315-00-4
IUPAC name
7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
State
State
The compound is a solid at room temperature, maintaining its crystalline form under normal conditions.
Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
700.00
Boiling point (Kelvin)
973.15
General information
Molecular weight
264.65g/mol
Molar mass
264.6990g/mol
Density
1.3524g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. The finely divided form ensures a uniform texture without any significant color impurities.

Comment on solubility

Solubility of 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

The solubility of 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one is influenced by various factors due to its complex molecular structure. Generally, the following points should be considered:

  • Polarity: Compounds with polar functional groups tend to be more soluble in polar solvents, while non-polar compounds are typically soluble in non-polar solvents.
  • Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding can significantly enhance its solubility in water.
  • Molecular Size: Larger molecules may exhibit lower solubility due to steric hindrance, which can impede interaction with solvent molecules.

The solubility data for this compound might not be readily available, but it is important to recognize that:

  • The presence of the isoxazole ring system can add to its polarity, which may favor solubility in polar solvents.
  • The chloro and methyl substituents could impact the overall solubility, modifying the compound's interactions with solvation shells.
  • In general, one might expect the solubility to be higher in organic solvents as opposed to strictly aqueous environments due to structural complexities.

In summary, the solubility of 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one is subject to various chemical interactions and environmental conditions. Comprehensive experimental data would provide a clearer picture of its solubility profile.

Interesting facts

Interesting Facts about 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

The compound known as 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one is a fascinating example of organic chemistry, particularly within the realm of heterocyclic compounds. Its intricate structure presents numerous opportunities for study and application.

Key Features:

  • Structure Variety: This compound features a unique isoxazole ring structure fused with a benzoxazine, showcasing significant chemical diversity.
  • Chlorine Substitution: The presence of chlorine at the 7-position makes it an interesting candidate for further reactions, as chlorine can influence reactivity and solubility.
  • Potential Applications: Compounds of this type have been investigated for their biological activity, potentially serving as pharmaceuticals or agrochemicals.

As stated in a study, "The synthesis and characterizations of such complex heterocycles provide insights into the evolution of compounds with specific biological activities." This highlights the role of compounds like 7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one in advancing medicinal chemistry.

Moreover, the dihydro version of the isoxazole ring may exhibit unique properties compared to its saturated counterparts, making it a subject of interest for chemists seeking novel chemical behaviors. With ongoing research, the full potential of this compound, including its reactivity and possible applications in drug development, is yet to be fully explored.

Synonyms
Meseclazone
29053-27-8
Meseclazona
W-2395
Meseclazonum
51KFT71THG
NSC-297623
DTXSID70865466
7-Chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one
2H,9H-Isoxazolo(3,2-b)(1,3)benzoxazin-9-one, 7-chloro-3,3a-dihydro-2-methyl-
2H,9H-Isoxazolo[3,2-b][1,3]benzoxazin-9-one, 7-chloro-3,3a-dihydro-2-methyl-
RefChem:925532
DTXCID60813870
NSC297623
W 2395
7-chloro-2-methyl-3,3a-dihydro-2H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one
2H,9H-ISOXAZOLO(3,2-b)(1,3)BENZOXAZIN-9-ONE, 3,3a-DIHYDRO-7-CHLORO-2-METHYL-
W2395;NSC297623
Meseclazone [USAN:INN]
Meseclazonum [INN-Latin]
Meseclazona [INN-Spanish]
UNII-51KFT71THG
NSC 297623
MESECLAZONE [INN]
Meseclazone (USAN/INN)
MESECLAZONE [USAN]
7-Chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one
SCHEMBL43495
orb1706900
CHEMBL2104738
SCHEMBL29463844
OJGJQQNLRVNIKE-UHFFFAOYSA-N
EBA05327
HY-U00157
AKOS040742317
CS-7203
2H,9H-Isoxazolo(3,2-b)(1,3)benzoxacin-9-one, 7-chloro-3,3a-dihydro-2-methyl-
DA-75426
NS00124072
D04941
Q6821182
2H,2-b][1,3]benzoxacin-9-one, 7-chloro-3,3a-dihydro-2-methyl-
2H,2-b][1,3]benzoxazin-9-one, 7-chloro-3,3a-dihydro-2-methyl-
7-chloro-2-methyl-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
7-chloro-2-methyl-3,3a-dihydro-2H, 9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one
7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one
7-CHLORO-3,3A-DIHYDRO-2-METHYL-2H,9H-ISOXAZOLO(3,2-.BETA.)(1,3)BENZOXAZIN-9-ONE
7-chloro-3,3a-dihydro-2-methyl-2h,9h-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one
2H,9H-ISOXAZOLO(3,2-.BETA.)(1,3)BENZOXACIN-9-ONE, 7-CHLORO-3,3A-DIHYDRO-2-METHYL-