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Clonazolam

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Identification
Molecular formula
C24H23ClN4O4
CAS number
33887-02-4
IUPAC name
[7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate
State
State

Clonazolam is a solid at room temperature. It is generally available in powdered form, which facilitates its use in various chemical and pharmacological applications. Due to its nature as a potent compound, it is typically handled in very small quantities.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
427.89g/mol
Molar mass
427.8880g/mol
Density
1.3000g/cm3
Appearence

Clonazolam is typically a crystalline powder. It can appear as either white or off-white in color, though the exact color may vary slightly depending on purity and specific form. The crystalline nature of the compound is due to its specific molecular structure.

Comment on solubility

Solubility of [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate

The solubility of [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate can be influenced by various factors due to its complex molecular structure. Here are some key points regarding its solubility:

  • Solvent Dependence: Compounds of this nature typically exhibit varying solubility in polar vs. non-polar solvents. It may be more soluble in solvents like ethanol or methanol rather than in hydrocarbons.
  • pH Sensitivity: The ionization state of the compound can change with pH, potentially affecting its solubility. For instance, the presence of acidic or basic conditions may lead to better dissolution due to the formation of charged species.
  • Temperature Influence: As with many organic compounds, solubility often increases with higher temperatures. This could be beneficial in extraction or formulation processes.
  • Cyclic Structure Considerations: The presence of the benzodiazepine ring may contribute to a more hydrophobic character, which typically reduces water solubility.

In conclusion, the solubility of [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate is not straightforward and is influenced by a combination of chemical structure, solvent interactions, and environmental conditions. Always consider these factors when working with this compound in laboratory settings.

Interesting facts

Interesting Facts about [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate

The compound [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate is a fascinating entity within the realm of pharmaceuticals and organic chemistry. As a member of the benzodiazepine family, this compound is noteworthy for several reasons:

  • Pharmacological Potential: Compounds in the benzodiazepine class are well-known for their role as anxiolytics, sedatives, and muscle relaxants. This particular structure hints at potential psychoactive properties, which can lead to new therapeutic developments.
  • Structure-Activity Relationship: The intricate arrangement of functional groups in this compound, including the 7-chloro and 3,4,5-trimethoxy groups, makes it an interesting subject for understanding how chemical modifications affect biological activity.
  • Research Interest: Due to its complex structure, it invites extensive investigative studies. Researchers are continually exploring its synthesis and the mechanisms by which it may exhibit its pharmacological effects.
  • Chemical Stability: The stability of benzodiazepine derivatives, including this compound, can vary significantly depending on the substituents. This variability prompts further inquiries into its stability under various conditions.
  • Medicinal Chemistry: The design and synthesis of such compounds are pivotal in medicinal chemistry, highlighting the interplay between organic synthesis and biological function. The detailed study of this compound can contribute to advancements in drug development.

In summary, [7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-3-yl] 3,4,5-trimethoxybenzoate exemplifies the complexities and potentials within chemical research. As scientists delve deeper into its properties and effects, exciting discoveries await!