Skip to main content

Etifoxine

ADVERTISEMENT
Identification
Molecular formula
C17H19ClN2O
CAS number
21743-07-1
IUPAC name
7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine
State
State

Etifoxine is typically solid at room temperature.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
655.00
Boiling point (Kelvin)
928.15
General information
Molecular weight
300.80g/mol
Molar mass
300.8220g/mol
Density
1.2331g/cm3
Appearence

Etifoxine typically appears as a white or off-white crystalline powder. It is known for its purity in the pharmaceutical industry.

Comment on solubility

Solubility of 7-Chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine

The solubility of 7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine in various solvents is a critical characteristic that affects its application in different chemical processes. Understanding its solubility can help predict its behavior in biological systems and influence formulation strategies.

Key Points on Solubility:

  • Polar Solvents: The presence of polar functional groups in the compound suggests moderate solubility in water and other polar solvents.
  • Non-Polar Solvents: Due to its benzoxazine structure, the compound may exhibit limited solubility in non-polar solvents.
  • pH Dependency: The solubility can also vary with pH, which means that using acidic or basic conditions may enhance or reduce its solubility.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, predicting better solubility at elevated temperatures.

In summary, the solubility profile of 7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine is influenced by various factors. Understanding these interactions is essential for optimizing its usage in pharmaceuticals and materials science. As the saying goes, "Solubility is key to activity," emphasizing the importance of comprehensively studying this compound's solubility characteristics.

Interesting facts

Interesting Facts about 7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine

This intriguing compound belongs to the class of benzoxazines, which are noteworthy for their diverse applications in medicinal chemistry and materials science. Below are some interesting points that highlight its significance:

  • Mechanism of Action: Compounds like 7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine often interact with neurotransmitter receptors. This particular structure suggests potential relevance in therapeutic areas such as analgesia and neuroprotection.
  • Synthetic Versatility: The synthesis of benzoxazines can often involve simple steps and versatile routes, making them attractive targets for research laboratories. The integration of piperidyl groups enhances the chemical reactivity, offering a pathway for further modifications.
  • Potential Applications: Beyond medicinal uses, benzoxazines have found roles in polymer science due to their thermosetting properties. Their ability to form cross-linking networks makes them integral in the development of high-performance materials.
  • Research Highlight: Scientists have been exploring the neuropharmacological effects of piperidine derivatives extensively. The presence of the 1-piperidyl moiety in this compound may hint at valuable binding interactions that could unfold in future studies.
  • Key Structural Features: The combination of a chloro group and a benzoxazine ring contributes to the compound's reactivity, while also impacting its lipophilicity and biological interactions. This balance is crucial in developing compounds that are both effective and safe.

As we continue to explore the chemical landscape, compounds such as 7-chloro-3-[2-(1-piperidyl)ethyl]-1,4-dihydro-2,3-benzoxazine show great promise in bridging gaps between basic research and therapeutic applications. Understanding its properties and potential could lead to innovative breakthroughs in chemistry and medicine.