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Oxymetazoline Hydrochloride

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Identification
Molecular formula
C16H24ClN3O2
CAS number
2315-02-8
IUPAC name
7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride
State
State

Oxymetazoline Hydrochloride is typically encountered in a solid state under room temperature conditions. It is often formulated into nasal sprays or other aqueous solutions for medical use, primarily as a decongestant.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
406.15
Boiling point (Kelvin)
679.30
General information
Molecular weight
296.20g/mol
Molar mass
296.1990g/mol
Density
1.0000g/cm3
Appearence

Oxymetazoline Hydrochloride appears as a white to off-white crystalline powder. It is generally very fine and has a slight characteristic odor. The powder is highly soluble in water, making it suitable for various pharmaceutical formulations.

Comment on solubility

Solubility of 7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride

The solubility of 7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride is influenced by its unique chemical structure, which includes a quaternary ammonium group. This compound is expected to exhibit notable solubility characteristics due to the following factors:

  • Ionization: The presence of the piperidinium ion increases water solubility as ionic compounds generally dissolve well in polar solvents.
  • Polarity: The benzoxazin structure adds polar functional groups, further enhancing solubility in aqueous environments.
  • Electrostatic Interactions: The dichloride form of the compound can interact with water molecules, facilitating its solvation.

However, the solubility may vary under different conditions, such as:

  • Temperature: Higher temperatures typically increase solubility.
  • pH Levels: As an ionic compound, its solubility might be affected by the acidity or basicity of the solution.
  • Presence of Other Solvents: Organic solvents may also influence solubility by altering solvation dynamics.

In conclusion, while 7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride is likely to have good solubility in water, it is essential to consider these influencing factors to better understand its behavior in various environments.

Interesting facts

Exploring 7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride

This fascinating compound belongs to a class of chemicals known for their unique interactions with biological systems. Often called a quaternary ammonium compound due to its positively charged nitrogen atom, this compound demonstrates intriguing properties worth discussing.

Interesting Insights

  • Bioactivity: Compounds similar to this one may exhibit significant biological activity, making them candidates for potential pharmaceutical applications. Researchers are keen on exploring their roles in medicinal chemistry.
  • Synthetic Utility: The structure is notable for its complex ring system combined with nitrogen functionalities, which could serve as a scaffold for further chemical modifications.
  • Research Applications: Ongoing studies consider the potential of the benzoxazine core in developing new materials, particularly in polymer chemistry, due to its reactive nature and ability to cross-link.
  • Piperidine Influence: The presence of the piperidine moiety adds a unique aspect to the compound's properties, often enhancing solubility and modifying lipophilicity, which are critical for drug design.

In the words of a famous chemist, "Chemistry knows no boundaries." This compound is an excellent reminder of the endless possibilities that lie within the molecular world. Whether in drug development or material science, 7-chloro-3-(2-piperidin-1-ium-1-ylethyl)-3,4-dihydro-1H-2,3-benzoxazin-3-ium;dichloride presents a rich area for exploration and discovery!

Synonyms
21977-22-0
1H-2,3-Benzoxazine, 7-chloro-3,4-dihydro-3-(2-piperidinoethyl)-, dihydrochloride
1H-2,3-BENZOXAZINE, 3,4-DIHYDRO-7-CHLORO-3-(2-PIPERIDINOETHYL)-, DIHYDROCHLORIDE
RefChem:1057764
7-Chloro-3-(2-piperidinoethyl)-3,4-dihydro-1H-2,3-benzoxazine dihydrochloride