Interesting facts
Interesting Facts about 7-Chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
This fascinating compound, often known for its role in medicinal chemistry, belongs to a class of compounds known as benzothiadiazines. Here are some intriguing insights about this compound:
- Pharmaceutical Applications: One of the most notable properties of this compound is its utility in the synthesis of pharmaceutical agents. Its structure allows it to interact effectively with biological systems, making it a candidate for various therapeutic applications.
- Chlorine Atom Influence: The presence of the chlorine atom in its structure significantly enhances its biological activity. Chlorine substitutions in organic compounds can influence metabolic stability and efficacy.
- Mechanism of Action: Compounds in the benzothiadiazine family are known to act on specific receptors. For instance, they can serve as antagonists for certain neurotransmitter receptors, which can lead to potential applications in treating neurological disorders.
- Environmental Considerations: The persistence of organic compounds like this one in the environment raises questions about their ecological impact. Understanding the degradation pathways of such compounds is crucial for assessing their safety.
- Research Potential: Ongoing research continues to explore the modification of benzothiadiazine structures to improve their pharmacological profiles. This opens the door to novel drug development strategies.
As chemists delve deeper into the properties and reactions of 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide, the potential for discovering new therapeutic avenues is both exciting and promising. This compound exemplifies how small changes in molecular structure can lead to significant biological effects.
Synonyms
diazoxide
364-98-7
Proglycem
Hyperstat
Hypertonalum
Eudemine
Proglicem
Dizoxide
Mutabase
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Diazossido
Diazoxido
Diazoxidum
Sch 6783
Sch-6783
SRG 95213
SRG-95213
C8H7ClN2O2S
Eudemine injection
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
NSC-64198
Diazoxidum [INN-Latin]
Diazoxido [INN-Spanish]
NSC 76130
CHEBI:4495
UNII-O5CB12L4FN
EINECS 206-668-1
O5CB12L4FN
MFCD00078578
NSC 64198
NSC-76130
DTXSID7022914
3-methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
NSC64198
NSC76130
MLS000028459
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine1,1-dioxide
DTXCID902914
364-98-7 (free)
7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide
Diazossido [Italian]
Diazoxide [USAN:USP:INN:BAN:JAN]
7-chloro-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide
Diazossido [DCIT]
NCGC00015380-09
CAS-364-98-7
SMR000058392
Diazoxidum (INN-Latin)
Diazoxido (INN-Spanish)
DIAZOXIDE (MART.)
DIAZOXIDE [MART.]
DIAZOXIDE (USP-RS)
DIAZOXIDE [USP-RS]
DIAZOXIDE (EP MONOGRAPH)
DIAZOXIDE [EP MONOGRAPH]
DIAZOXIDE (USP MONOGRAPH)
DIAZOXIDE [USP MONOGRAPH]
Aroglycem
7-Chloro-3-methyl-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
Diazoxide (USAN:USP:INN:BAN:JAN)
Hyperstat (TN)
SR-01000075314
7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide
Diazoxide (JAN/USP/INN)
Eudimine
2H-1,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
Proglycem (TN)
Prestwick_163
Diazoxide (Standard)
Diazoxide Oral Solution
Tocris-0964
DIAZOXIDE [INN]
DIAZOXIDE [JAN]
Opera_ID_608
DIAZOXIDE [MI]
DIAZOXIDE [USAN]
Diazoxide Oral Suspension
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Spectrum3_000735
Spectrum4_001248
DIAZOXIDE [VANDF]
Lopac-D-9035
CHEMBL181
D 9035
DIAZOXIDE [WHO-DD]
DIAZOXIDE [WHO-IP]
CBiol_001750
Lopac0_000404
SCHEMBL41254
BSPBio_000014
BSPBio_001307
BSPBio_002290
KBioGR_000027
KBioGR_001776
KBioSS_000027
MLS001076071
MLS001424164
SPECTRUM2300206
SPBio_001953
BPBio1_000016
GTPL2409
DIAZOXIDE [ORANGE BOOK]
CHEMBL1518123
BDBM86248
HY-B1140R
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
C02DA01
V03AH01
DIAZOXIDUM [WHO-IP LATIN]
7-chloro-3-methyl-4h-1|E6,2,4-benzothiadiazine 1,1-dioxide
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
HMS2095A16
HMS2234B23
HMS3261A10
HMS3267I11
HMS3371L13
HMS3393P20
HMS3402B09
HMS3411L18
HMS3675L18
HMS3712A16
HMS3885H12
Pharmakon1600-02300206
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
BCP26107
HY-B1140
NSC_3019
Tox21_110132
Tox21_500404
BDBM50237612
HB0244
KC-115
NSC759574
s4630
AKOS015896340
AKOS024458715
Tox21_110132_1
CCG-101062
CCG-204497
CS-4745
DB01119
FD21519
KS-1444
LP00404
NC00312
NSC-759574
SDCCGSBI-0050390.P002
IDI1_033777
Diazoxide 100 microg/mL in Acetonitrile
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-04
NCGC00015380-05
NCGC00015380-06
NCGC00015380-07
NCGC00015380-08
NCGC00015380-10
NCGC00015380-11
NCGC00015380-12
NCGC00015380-13
NCGC00015380-20
NCGC00022882-03
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
NCGC00261089-01
CAS_364-98-7
SY066792
DB-048966
D5402
EU-0100404
NS00008680
VU0239714-6
C06949
D00294
EN300-122611
F12855
Q420009
SR-01000075314-1
SR-01000075314-3
SR-01000075314-4
SR-01000075314-6
3-methyl-7-chloro-1,2,4-benzothiadiazine1,1-dioxide
BRD-K73109821-001-05-2
BRD-K73109821-001-10-2
BRD-K73109821-001-19-3
BRD-K73109821-001-20-1
Z1269122570
Diazoxide, European Pharmacopoeia (EP) Reference Standard
4H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
7-chloro-3-methyl-2H-1lambda6,2,4-benzothiadiazine-1,1-dione
7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
Diazoxide, United States Pharmacopeia (USP) Reference Standard
7-chloro-3-methyl-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide
7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione
206-668-1
Solubility of 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide (C16H11ClN2O3S)
The solubility of 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide is an important characteristic that influences its applications in various fields, especially in medicinal chemistry. Understanding its solubility behavior provides insights into its bioavailability and potential effectiveness as a pharmaceutical agent.
Several factors can affect the solubility of this compound:
In practical terms, 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide is known to exhibit low solubility in water, making it crucial to explore alternative methods for enhancing its solubility, such as:
In conclusion, solubility plays a pivotal role in the efficacy of 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide, and thorough knowledge of its solubility characteristics will facilitate its application in scientific research and pharmaceutical development.