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7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

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Identification
Molecular formula
C11H7ClN2O3
CAS number
2332559-63-2
IUPAC name
7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
State
State

At room temperature, this compound exists in a solid state. It is stable under standard conditions and does not readily evaporate or dissolve in water.

Melting point (Celsius)
151.50
Melting point (Kelvin)
424.65
Boiling point (Celsius)
305.80
Boiling point (Kelvin)
578.95
General information
Molecular weight
238.64g/mol
Molar mass
238.6500g/mol
Density
1.6900g/cm3
Appearence

This compound typically appears as a crystalline solid with a distinct white to off-white color, indicating its purity and form at ambient conditions.

Comment on solubility

Solubility of 7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

The solubility of 7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one can be influenced by several factors due to its complex molecular structure. Key points to consider include:

  • Polarity: The compound possesses polar functional groups which may enhance its solubility in polar solvents such as water and alcohols.
  • Solvent Interaction: Solubility can greatly vary depending on the solvent used. For instance, it may be more soluble in solvents like dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) compared to less polar solvents.
  • Temperature Dependency: Generally, solubility can increase with rising temperature; hence, heating the solvent might improve compound dissolution.
  • pH Levels: The pH of the solution may also affect solubility. For ionizable compounds, an increase in pH may enhance solubility by deprotonating acidic groups.

In practical applications, understanding these factors is essential for maximizing the utilization of this compound in various formulations. As noted, "the right environment can significantly enhance the accessibility of a compound," making solubility a critical consideration in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one is a fascinating compound that belongs to the family of benzoxazines, a class of compounds known for their varied applications in materials science and medicinal chemistry. Here are some intriguing points about this unique chemical:

  • Antimicrobial Properties: Research has shown that compounds similar to this one exhibit significant antimicrobial activity, making them candidates for pharmaceutical developments aimed at combating bacterial infections.
  • Structural Innovation: The intricate bicyclic structure of the compound allows for interesting interactions at the molecular level, prompting studies into its mechanisms of action and potential therapeutic effects.
  • Role in Organic Synthesis: Benzoxazines, including this compound, are often explored as precursors in organic synthesis, facilitating the creation of a diverse array of chemical entities.
  • Versatile Applications: The unique properties of isoxazoles suggest their roles in various domains like material sciences, particularly in the development of high-performance polymers and coatings.

This compound serves as an excellent example of how variations in chemical structure can lead to significant changes in physical and chemical properties, illustrating the **beauty of chemistry** and its impact on various scientific advancements. As a chemistry student, delving into such compounds can spark innovation and encourage further exploration in the ever-evolving field of chemistry.

Synonyms
Seclazone
29050-11-1
Seclazona
Seclazonum
W-2354
JW3UZ4I1A8
NSC-294833
W-2352
7-Chloro-3,3a-dihydro-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one
RefChem:884782
W 2354
7-chloro-3,3a-dihydro-2H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one
2H,9H-ISOXAZOLO(3,2-b)(1,3)BENZOXAZIN-9-ONE, 3,3a-DIHYDRO-7-CHLORO-
NSC294833
Seclazone [USAN:INN]
Seclazonum [INN-Latin]
7-chloro-3,3a-dihydro-2H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
Seclazona [INN-Spanish]
2H,9H-Isoxazolo(3,2-b)(1,3)benzoxazin-9-one, 7-chloro-3,3a-dihydro-
2H,9H-Isoxazolo[3,2-b][1,3]benzoxazin-9-one, 7-chloro-3,3a-dihydro-
UNII-JW3UZ4I1A8
NSC 294833
BRN 1078684
MFCD00866036
SECLAZONE [INN]
Seclazone (USAN/INN)
SECLAZONE [USAN]
3,3a-Dihydro-7-chloro-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one
W 2352
SCHEMBL42938
orb1695239
CHEMBL2105593
DTXSID10865465
EX-A4408
AKOS027201110
DA-57766
MS-23274
HY-119517
CS-0068623
NS00126774
D05810
EN300-254363
G12723
BRD-A53472930-001-01-7
Q27281717
Z1509534676
2H,2-b][1,3]benzoxazin-9-one, 7-chloro-3,3a-dihydro-
7-chloro-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one
11-chloro-2,6-dioxa-7-azatricyclo[7.4.0.0,3,7]trideca-1(13),9,11-trien-8-one
11-chloro-2,6-dioxa-7-azatricyclo[7.4.0.0?,?]trideca-1(13),9,11-trien-8-one