Interesting facts
Interesting Facts about 7-Chloro-4-Hydroxy-5-Phenyl-3H-1,4-Benzodiazepin-2-One
The compound 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one is a noteworthy member of the benzodiazepine family, which is widely recognized for its pharmacological significance. This specific compound stands out for several reasons:
- Pharmacological Activity: Compounds related to benzodiazepines are primarily known for their sedative, anxiolytic, and muscle relaxant properties. The presence of the chloro and hydroxyl groups at specific positions in the molecular structure often contributes to its effectiveness in treating anxiety disorders.
- Research and Development: This compound continues to be the subject of research, delving into its potential therapeutic applications beyond traditional uses, such as in treating neurodegenerative diseases or enhancing cognitive function.
- Structure-Activity Relationship: The intricate structure of 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one allows chemists to explore how modifications to specific functional groups can influence the compound's efficacy and side effects, paving the way for the development of better medications.
- Historical Significance: As a derivative of benzodiazepine, this compound is part of a larger class of medications that revolutionized the management of anxiety and insomnia since their introduction into medicine in the mid-20th century.
In the words of chemist and Nobel laureate Robert F. Furchgott: "We stand on the shoulders of giants." The continued study of compounds like 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one not only honors the legacy of past research but also opens doors for new therapeutic advancements.
As the field of medicinal chemistry evolves, understanding the functionalities of such compounds is essential for progress. Through further investigation, we may unlock new potential benefits that could significantly improve the lives of patients worldwide.
Synonyms
Demoxepam
963-39-3
Chlordiazepoxide lactam
Ro 5-2092
Demossepam [DCIT]
Demoxepamum
NSC-46077
Demossepam
Demoxepam [USAN:INN]
Demoxepamum [INN-Latin]
NSC 46077
NSC 169898
2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1,3-DIHYDRO-5-PHENYL-, 4-OXIDE
EINECS 213-515-2
8X1XP5M0SB
NSC-169898
BRN 0755892
DTXSID4046155
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
DEMOXEPAM [INN]
DEMOXEPAM [USAN]
NSC-46007
Ro-52092
RO-5-2092
DTXCID2026155
1,3-Dihydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one-4-oxide
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-, 4-oxide
5-24-04-00295 (Beilstein Handbook Reference)
OXAZEPAM IMPURITY E [EP IMPURITY]
Demoxepamum (INN-Latin)
7-Chloro-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 4-oxide
CHLORDIAZEPOXIDE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
5-PHENYL-7-CHLORO-3H-1,4-BENZODIAZEPIN-2(1H)-ONE 4-OXIDE
7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide
OXAZEPAM IMPURITY E (EP IMPURITY)
CHLORDIAZEPOXIDE HYDROCHLORIDE IMPURITY A (EP IMPURITY)
213-515-2
7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-one-4-oxide
7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one
Ro 5-2092 lactam
NSC46077
NSC169898
Ro 52092
NCGC00160447-01
RO5-2092
Demoxepam (1mg/ml in Acetonitrile)
7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-Oxide (Demoxepam)
WLN: T67 GMV JN IHJ CG JO KR
7-Chloro-1,4-benzodiazepin-2-one 4-oxide
7-Chloro-1,4-benzodiazepin-2-one-4-oxide
2H-1, 7-chloro-1,3-dihydro-5-phenyl-, 4-oxide
UNII-8X1XP5M0SB
Demoxepam (Standard)
BAS 03296481
Demoxepam (USAN/INN)
ChemDiv1_028594
Chlordiazepoxide impurity A
SCHEMBL78342
MLS001209924
CHEMBL1597677
HMS668D16
Demoxepam 1.0 mg/ml in Methanol
PSADRZMLSXCSAS-UHFFFAOYSA-N
Demoxepam, 1mg/ml in Acetonitrile
HMS2832C15
ARD10277
Tox21_111817
STL044774
7-Chloro-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide
AKOS000638527
AKOS005700135
HY-136591R
Demoxepam (1.0 mg/mL in Acetonitrile)
1ST10277
CAS-963-39-3
MS-24096
SMR000518461
DB-080423
HY-136591
CS-0131905
NS00015681
D02600
G12766
CHLORDIAZEPOXIDE IMPURITY A [EP IMPURITY]
EN300-18220459
SR-01000357383
Q5256385
SR-01000357383-1
Z56890974
7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-ol 4-oxide
2H-1, 4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-, 4-oxide
7-Chloro-1,3-dihydro-5-phenyl-2H-1, 4-benzodiazepin-2-one 4-oxide
7-Chloro-1,3-dihydro-5-phenyl-2H-1, 4-benzodiazepin-2-one-4-oxide
7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-4-ium-4-olate
7-chloro-4-oxido-5-phenyl-1,3-dihydro-[1,4]benzodiazepin-4-ium-2-one
7-chloro-4-oxido-5-phenyl-1,3-dihydro-1,4-benzodiazepin-4-ium-2-one
7-chloro-4-oxido-5-phenyl-1,5-dihydro-1,4-benzodiazepin-4-ium-2-one
7-Chloro-4-hydroxy-5-phenyl-1,3-dihydro-2H-1,4lambda~5~-benzodiazepin-2-one
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide5-phenyl-7-chloro-3H-1,4-benzodiazepin-2(1H)-one 4-oxide;7-Chloro-2, 3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 4-oxide;Chlordiazepoxide lactam
Solubility of 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one
The solubility of 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one is a nuanced characteristic that depends on several factors. This compound exhibits varying solubility in different solvents, which is an important aspect to consider in both practical applications and research. Here are some key points to consider:
It is often stated that "solubility is the key to understanding chemical behavior." Consequently, determining the solubility of 7-chloro-4-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one is vital for its applications in medicinal chemistry and pharmacology.
In summary, when evaluating the solubility of this compound, always consider:
The solubility profile can greatly influence the bioavailability and therapeutic efficacy of this compound in pharmaceutical applications.