Interesting facts
Interesting Facts about 7-Chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine; Hydrochloride
This compound is a member of the benzodiazepine family, which is renowned for its psychoactive effects. Here are some compelling aspects of this intriguing compound:
- Pharmacological Significance: Benzodiazepines are widely used in medicine for their anxiolytic, sedative, and anticonvulsant properties. This compound may exhibit similar pharmacological effects, contributing to its relevance in research and therapeutic applications.
- Mechanism of Action: Like other benzodiazepines, this compound is believed to enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, leading to increased inhibitory CNS effects.
- Structure-Activity Relationship: The unique substitution pattern on the benzodiazepine core plays a crucial role in determining the compound's potency and efficacy. The presence of the chloro group and the hydroxyl group can significantly affect its biological properties.
- Research Applications: This compound serves as a valuable tool in the study of neurotransmitter systems and drug interactions, making it a subject of interest for pharmacologists and neuroscience researchers alike.
- Potential Side Effects: As with many compounds in its class, caution is paramount due to possible side effects, including dependence, withdrawal symptoms, and cognitive impairment. Understanding these risks is crucial for safe therapeutic use.
- Historical Context: The discovery of benzodiazepines revolutionized the treatment of anxiety and sleep disorders in the mid-20th century, establishing a legacy of ongoing research into their derivatives and analogs.
In summary, 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine; hydrochloride is not just a chemical compound, but a window into the complexities of neuropharmacology and medicinal chemistry, highlighting the delicate balance between efficacy and safety in drug development.
Synonyms
CHLORDIAZEPOXIDE HYDROCHLORIDE
Clopoxide chloride
438-41-5
Librium
Chlordiazachel
Calmoden
Chlordiazepoxide Hcl
Protensin
Contol
Retcol
Chlordiazepoksid
A-Poxide
Droxol hydrochloride
Lygen
Napoton hydrochloride
Libritabs hydrochloride
Risachief hydrochloride
SK-Lygen
Ro 5-0690
Chlorodiazepoxide hydrochloride
Chlordiazepoxide monohydrochloride
Methaminodiazepoxide hydrochloride
MFM6K1XWDK
NSC-115748
7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride
3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride
Ro-5-0690
Benzodiapin
Ansiacal
Equibral
Labican
Lentotran
Novosed
Psichial
Reliberan
Sophiamin
Tensinyl
Timosin
Trakipeal
Viansin
Cebrum
Murcil
Seren vita
J-Liberty
Diazachel (Obs.)
Librium hydrochloride
UNII-MFM6K1XWDK
EINECS 207-117-8
NSC 115748
7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine;hydrochloride
component of Librax
Librium (TN)
Librium, hydrochloride
SCHEMBL8935
Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN]
Chloridiazepoxide hydrochloride
Methaminodiazepine hydrochloride
CHEBI:3612
CHEMBL1200703
PRNVHVUEIITLRV-UHFFFAOYSA-N
NSC115748
AKOS015895152
3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride
7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide hydrochloride
CHLORDIAZEPOXIDE HYDROCHLORIDE CIV
Chlordiazepoxide hydrochloride (JAN/USP)
CHLORDIAZEPOXIDE HYDROCHLORIDE [MI]
CHLORDIAZEPOXIDE HYDROCHLORIDE [JAN]
DB-051172
CHLORDIAZEPOXIDE HYDROCHLORIDE [USAN]
CHLORDIAZEPOXIDE HYDROCHLORIDE [VANDF]
NS00080080
CHLORDIAZEPOXIDE HYDROCHLORIDE [MART.]
C-2992
CHLORDIAZEPOXIDE HYDROCHLORIDE [USP-RS]
CHLORDIAZEPOXIDE HYDROCHLORIDE [WHO-DD]
D00693
WLN: T67 GN JN IHJ CG HM1 JO KR &GH
CHLORDIAZEPOXIDE HYDROCHLORIDE CIV [USP-RS]
CHLORDIAZEPOXIDE HYDROCHLORIDE [EP MONOGRAPH]
CHLORDIAZEPOXIDE HYDROCHLORIDE [ORANGE BOOK]
CHLORDIAZEPOXIDE HYDROCHLORIDE [USP MONOGRAPH]
Q27106148
3H-1, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride
7-Chloro-2-(methylamino)-5-phenyl-3H-1, 4-oxide, hydrochloride
Chlordiazepoxide hydrochloride, drug standard, 1.0 mg/mL in methanol
3H-1, 7-chloro-2-(methylamino)-5-phenyl-, 4-oxide, monohydrochloride
7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine-4-oxide hydrochloride
7-chloro-2-(methylamino)-5-phenyl-3H-benzo[e][1,4]diazepine 4-oxide hydrochloride
Chlordiazepoxide hydrochloride, European Pharmacopoeia (EP) Reference Standard
Chlordiazepoxide hydrochloride, United States Pharmacopeia (USP) Reference Standard
Solubility of 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine; hydrochloride
The solubility of 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine; hydrochloride can be fascinating to investigate. This compound is classified as a hydrochloride salt, which generally enhances its solubility in polar solvents compared to its free base form. Here are some key points to consider:
In summary, for 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine; hydrochloride, one might expect a higher solubility in polar environments, providing that the right conditions, such as pH and solvent type, are maintained. Understanding these solubility characteristics is important for practical applications, such as drug formulation and bioavailability studies.