Skip to main content

Clonazepam

ADVERTISEMENT
Identification
Molecular formula
C15H11ClN4O2
CAS number
1622-62-4
IUPAC name
(7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride
State
State

At room temperature, this compound is typically found in a solid state, existing as a crystalline powder.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
316.72g/mol
Molar mass
316.7090g/mol
Density
1.4200g/cm3
Appearence

This compound typically appears as a white to slightly yellowish crystalline powder. It is odorless or nearly odorless.

Comment on solubility

Solubility of (7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride

The solubility of the compound (7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride is influenced by various factors, including its ionic nature and molecular structure. This compound is a salt, and as such, several characteristics contribute to its solubility:

  • Ionic Interaction: Being a quaternary ammonium salt, it tends to dissolve well in water due to strong ionic interactions.
  • Polarity: The presence of the chloro and oxido groups enhances the compound's polarity, promoting solubility in polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding with water molecules further aids its solubility.

In general, ionic compounds like this one exhibit high solubility in water, making them readily available for various applications. It can be noted that:

  1. Solubility may vary: Although it is likely to be soluble in aqueous solutions, the specific solubility value should be confirmed through empirical testing.
  2. Temperature Dependence: The solubility may also change with temperature; typically, higher temperatures increase solubility.
  3. Effect of pH: The solubility in biological systems may depend on the pH level due to potential binding interactions with biological molecules.

In summary, while specific experimental conditions may affect the solubility of (7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride, it is primarily expected to exhibit favorable solubility owing to its ionic characteristics and the influence of functional groups throughout its molecular structure.

Interesting facts

Intriguing Insights into (7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride

This chemical compound is a fascinating member of the benzodiazepine family, known for its pharmacological importance. Benzodiazepines are mainly recognized for their effectiveness as anxiolytics, sedatives, and muscle relaxants, making them significant in medicinal chemistry.

Here are some interesting aspects of this compound:

  • Pharmacological Relevance: The structural components of this compound suggest potential uses in the treatment of anxiety disorders, demonstrating the significance of modifying various functional groups.
  • Structure Activity Relationship (SAR): The presence of a chloride substituent and a phenyl group in its structure opens avenues for studying how small changes in chemical make-up can lead to altered biological activities.
  • Mechanism of Action: Compounds like this often interact with the GABAA receptor, enhancing the inhibitory effects of GABA, which is a neurotransmitter responsible for calming neuronal activity.
  • Research Applications: Due to its unique structure, researchers may utilize this compound in various studies, seeking to identify how modifications can produce different therapeutic effects.
  • History of Benzodiazepines: First introduced in the 1960s, benzodiazepines revolutionized the treatment of anxiety and insomnia, leading to a wide range of derivatives; this compound represents continued evolution in this field of chemistry.

Overall, (7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)ammonium;chloride exemplifies the intersection of organic chemistry and medicine, showcasing the importance of chemical structure in determining biological function. As ongoing research explores its potential applications further, this compound serves as a prime example of the versatility and richness of benzodiazepine derivatives.